
wklab.org
WK Lab Wouters Koritzinsky GroupThe adverse effects of tumour hypoxia on patient outcome are attributed to both the resistance of hypoxic cells to conventional therapy and to hypoxia-induced biological changes that promote a more malignant phenotype. Understanding molecular responses to hypoxia is therefore important to effectively predict and/or target tumour hypoxia in the clinic. Understanding how hypoxic response pathways influence the biology of tumor cells in ways that affect patient prognosis. The signaling pathways regulate...
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