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Systems Biology of Cell-Matrix Adhesion. Figure 1. Cell-matrix adhesion sites. Cell-matrix adhesion is mediated by dynamic and diverse sites along the plasma membrane at which transmembrane receptors of the integrin family anchor the actin cytoskeleton to components of the extracellular matrix via a multi-protein structure. The scheme is modified from Hoffmann et al., eLife 3:e02257 (2014). Figure 2. The integrin adhesome. 2017 Eli Zamir, www.cell-adhesion.com.
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