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CPIC

CPIC open meeting on 3/15/2017 in Washington DC – more details on the meetings page. The Clinical Pharmacogenetics Implementation Consortium (CPIC). Was formed as a shared project between PharmGKB. And the Pharmacogenomics Research Network (PGRN). CPIC guidelines are peer-reviewed and published in a leading journal (in partnership with Clinical Pharmacology and Therapeutics. Mary V. Relling, Pharm.D. St Jude Children’s Research Hospital, Memphis. Teri E. Klein, Ph.D. Brad Strock, Epic. December 14, 2016.

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CPIC | cpicpgx.org Reviews

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CPIC open meeting on 3/15/2017 in Washington DC – more details on the meetings page. The Clinical Pharmacogenetics Implementation Consortium (CPIC). Was formed as a shared project between PharmGKB. And the Pharmacogenomics Research Network (PGRN). CPIC guidelines are peer-reviewed and published in a leading journal (in partnership with Clinical Pharmacology and Therapeutics. Mary V. Relling, Pharm.D. St Jude Children’s Research Hospital, Memphis. Teri E. Klein, Ph.D. Brad Strock, Epic. December 14, 2016.

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CPIC | cpicpgx.org Reviews

https://cpicpgx.org

CPIC open meeting on 3/15/2017 in Washington DC – more details on the meetings page. The Clinical Pharmacogenetics Implementation Consortium (CPIC). Was formed as a shared project between PharmGKB. And the Pharmacogenomics Research Network (PGRN). CPIC guidelines are peer-reviewed and published in a leading journal (in partnership with Clinical Pharmacology and Therapeutics. Mary V. Relling, Pharm.D. St Jude Children’s Research Hospital, Memphis. Teri E. Klein, Ph.D. Brad Strock, Epic. December 14, 2016.

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cpicpgx.org

1

Guidelines – CPIC

https://cpicpgx.org/guidelines

Each CPIC guideline adheres to a standard format, and includes a standard system for grading levels of evidence linking genotypes to phenotypes. How to assign phenotypes to clinical genotypes, prescribing recommendations based on genotype/phenotype, and a standard system for assigning strength to each prescribing recommendation. The CPIC authorship guidelines. Were updated in June 2014. CPIC is a partnership between PharmGKB. CPIC is managed at Stanford University. St Jude Children's Research Hospital.

2

Alleles – CPIC

https://cpicpgx.org/alleles

Each allele in this table is discussed in the corresponding CPIC guideline manuscript or supplement listed below. CPIC is a partnership between PharmGKB. CPIC is managed at Stanford University. St Jude Children's Research Hospital. CPIC is a registered service mark of the US Department of Health and Human Services (HHS).

3

Meetings – CPIC

https://cpicpgx.org/meetings

March 15th, 2017. Washington Marriot Wardman Park, Washington, DC. The Clinical Pharmacogenetics Implementation Consortium (CPIC ) Meeting will be held on March 15, 2017, in conjunction with the 2017 Annual Meeting of the American Society for Clinical Pharmacology and Therapeutics (ASCPT) on March 15-18, 2017 (Washington, DC). To register, click here. 2017 ASCPT Annual Meeting. March 15-18, 2017. Washington Marriot Wardman Park, Washington, DC. To register, click here. St Jude Children's Research Hospital.

4

Resources – CPIC

https://cpicpgx.org/resources

This presentation describes CPIC, the underlying assumptions of CPIC guidelines, the guideline development process and how the guidelines can be implemented in a clinical setting. Overview Presentation (.pptx). View a list of current implementers. Term Standardization for Clinical Pharmacogenetic Test Results. Learn about CPIC’s Term Standardization Project. Logo image files that you can use for referring to CPIC. The images are in PNG. Logo without full name. Logo with full name.

5

Genes-Drugs – CPIC

https://cpicpgx.org/genes-drugs

CPIC assigns CPIC levels to genes/drugs with (1) PharmGKB Clinical Annotation Levels of Evidence. Of 1A, 1B, 2A and 2B, or (2) a PharmGKB PGx level. For FDA-approved drug labels of “actionable pgx”, “genetic testing recommended”, or “genetic testing required”, or (3) based on nomination to CPIC for consideration. View CPIC’s process for prioritizing genes/drugs. View CPIC’s levels for genes/drugs. On existing and planned gene/drug guidelines. CPIC is a partnership between PharmGKB.

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pharmgkb.blogspot.com

PharmGKB Blog: July 2016

http://pharmgkb.blogspot.com/2016_07_01_archive.html

Tuesday, July 26, 2016. Pharmacogenomics discussed in the Summer 2016 issue of Genome magazine. The current issue of Genome magazine. Includes the article "Determining a Drug Response". It also briefly covers CYP2C19. And its role in response to antidepressants and antipsychotics. Regarding breastfeeding infants. The codeine drug label also contains a black box warning regarding potential respiratory depression and death in CYP2D6 ultrarapid metabolizer children who receive codeine following tonsille...

pharmgkb.blogspot.com

PharmGKB Blog: April 2016

http://pharmgkb.blogspot.com/2016_04_01_archive.html

Wednesday, April 20, 2016. Introducing the new PharmGKB Cancer PGx Portal. PharmGKB has collected a number of resources for Cancer PGx into one easy location. There are tables with direct links to genes important for cancer drug response both for PD and PK, to cancer drug pathways, particular cancers that have PGx data, types of toxicities common to cancer drugs, and external resources. Anyone with expertise in the genes who wishes to develop these with us for publication in PG&G, please contact feedback.

upgx.eu

Links | Ubiquitous Pharmacogenomics (U-PGx)

http://upgx.eu/links

The Pharmacogenomics Knowledge Base. European Medicines Agency, CHMP Pharmacogenomics Working Party. Clinical Pharmacogenomics Implementation Consortium. 2nd UPGx Personalized Medicine Day. Implementing Pharmacogenomics in Europe: Design and Implementation Strategy of the Ubiquitous Pharmacogenomics Consortium. 1st UPGx Personalized Medicine Day in Granada, Spain. UPGx members participate at the 2016 Golden Helix Summer School. 1st UPGx Personalised Medicine Day, Granada, Spain.

geneyouin.ca

F.A.Q. | Geneyouin

https://www.geneyouin.ca/how-it-works/faq

Q: What is Pillcheck? Q: Why should a PGx-trained pharmacist review my Pillcheck report? A: To get the most out of Pillcheck, we include a review by a PGx-trained pharmacist, who will write a letter summarizing your results for your prescribing doctor. You may also share your report with a pharmacist of your choice. Q: Should I continue my medications while waiting for my test results? A: You should continue taking your medications as prescribed, unless your doctor suggests otherwise. A: The Pillcheck me...

pharmgkb.blogspot.com

PharmGKB Blog: December 2016

http://pharmgkb.blogspot.com/2016_12_01_archive.html

Wednesday, December 14, 2016. CPIC Guideline Update: CYP2D6, CYP2C19 and tricyclic antidepressants (TCAs). The 2016 update of the guidelines by the Clinical Pharmacogenetics Implementation Consortium ( CPIC. Regarding the use of pharmacogenetic tests for CYP2D6 and CYP2C19 in dosing tricyclic antidepressants (TCAs) have been accepted for publication in Clinical Pharmacology and Therapeutics. The accepted article can currently be viewed on the. The 2016 guideline update provides dosing recommendations:.

pharmgkb.blogspot.com

PharmGKB Blog: August 2016

http://pharmgkb.blogspot.com/2016_08_01_archive.html

Friday, August 26, 2016. PharmCAT poster to be presented at ASHG. At the American Society of Human Genetics annual meeting in October, PharmGKB will be presenting the new Pharmacogenomics Clinical Annotation Tool (PharmCAT) with our colleague, Dr. Marylyn Ritchie, who is pictured on the home page of the meeting website ( http:/ www.ashg.org/2016meeting/. We look forward to seeing everyone there! Links to this post. Tuesday, August 16, 2016. CPIC Meeting at ASCPT on March 15, 2017. The CPIC-PGRN Meeting i...

pharmgkb.blogspot.com

PharmGKB Blog: March 2016

http://pharmgkb.blogspot.com/2016_03_01_archive.html

Thursday, March 31, 2016. CPIC Informatics Working Group publishes article in JAMIA. An article from the Clinical Pharmacogenetics Implementation Consortium (CPIC) Informatics Working Group has now been published ahead-of-print. On the Journal of the American Medical Informatics Association (JAMIA) website. Within the paper, the authors discuss principles that will support the implementation of precision medicine, particularly pharmacogenomics, into routine clinical care. Read the paper on JAMIA:. James ...

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cpicpgx.org

CPIC

CPIC open meeting on 3/15/2017 in Washington DC – more details on the meetings page. The Clinical Pharmacogenetics Implementation Consortium (CPIC). Was formed as a shared project between PharmGKB. And the Pharmacogenomics Research Network (PGRN). CPIC guidelines are peer-reviewed and published in a leading journal (in partnership with Clinical Pharmacology and Therapeutics. Mary V. Relling, Pharm.D. St Jude Children’s Research Hospital, Memphis. Teri E. Klein, Ph.D. Brad Strock, Epic. December 14, 2016.

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