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DIAGRAM Consortium

We currently provide a list of DIAGRAM publications. Summary data is available for Morris et al (2012): Stage 1 GWAS and Stage 2 Metabochip. Also available are summary statistics for the trans-ethnic T2D GWAS meta-analysis as published in Mahajan et al. (2014). For access to these, please follow the links to the left.

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We currently provide a list of DIAGRAM publications. Summary data is available for Morris et al (2012): Stage 1 GWAS and Stage 2 Metabochip. Also available are summary statistics for the trans-ethnic T2D GWAS meta-analysis as published in Mahajan et al. (2014). For access to these, please follow the links to the left.
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DIAGRAM Consortium | diagram-consortium.org Reviews

https://diagram-consortium.org

We currently provide a list of DIAGRAM publications. Summary data is available for Morris et al (2012): Stage 1 GWAS and Stage 2 Metabochip. Also available are summary statistics for the trans-ethnic T2D GWAS meta-analysis as published in Mahajan et al. (2014). For access to these, please follow the links to the left.

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diagram-consortium.org diagram-consortium.org
1

DIAGRAM Consortium

http://www.diagram-consortium.org/downloads.html

The forms below provide access to association summary statistics for the DIAGRAMv3 GWAS meta-analysis, as published in Morris et al (2012). Stage 1 GWAS: Summary Statistics. Please note that the summary statistics presented in this file have NOT. Been corrected for a second round of genomic control after meta-analysis. However the P values in the Morris et al paper WERE. Double GC corrected. There are more details in the PDF below. Not to attempt to de-identify individual subjects. The data is made avail...

2

DIAGRAM Consortium

http://www.diagram-consortium.org/pub.html

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. 2012 Sep;44(9):981-90. doi: 10.1038/ng.2383. Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Individual GWAS contributed to DIAGRAM. Wellcome Trust Case Control Consortium. 2007 Jun 7;447(7145):661-78.

3

DIAGRAM Consortium

http://www.diagram-consortium.org/index.html

We currently provide a list of DIAGRAM publications. Summary data is available for Morris et al (2012): Stage 1 GWAS and Stage 2 Metabochip. Also available are summary statistics for the trans-ethnic T2D GWAS meta-analysis as published in Mahajan et al. (2014). For access to these, please follow the links to the left.

4

DIAGRAM Consortium

http://www.diagram-consortium.org/about.html

The DIAGRAM ( DIA. An incremental meta-analysis ("DIAGRAM v2" or "DIAGRAM ") adding GWA data from a further five studies (DGDG, KORA, Rotterdam, DeCODE, EUROSPAN for a total of 8,130 cases and 38,987 controls) together with extensive replication involving 20 other cohorts, was central to identification of a further 17 loci ( Voight et al, Nature Genetics 2010. Dupuis et al, Nature Genetics 2010. Saxena et al, Nature Genetics 2010. Cho et al, Nature Genetics 2012.

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py-merp.github.io py-merp.github.io

3. Detailed Workflow — MeRP 0.0.1 documentation

http://py-merp.github.io/workflow.html

MeRP 0.0.1 documentation. 31 Obtaining Genetic Instruments from Public Data. Polarize’ the effect sizes given according to the unit syntax provided. 32 Linkage Disequilibrium (LD) and Confounding Association Filtering. For the IVF to satisfy conditions of MR analysis, MeRP provides filtering steps for LD and confounding trait associations. 321 Development of Metabolic P-val file. NA”). Final, filtered instrumental variable files (IVF) will contain the number of `. 322 Obtaining LD-query information.

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We currently provide a list of DIAGRAM publications. Summary data is available for Morris et al (2012): Stage 1 GWAS and Stage 2 Metabochip. Also available are summary statistics for the trans-ethnic T2D GWAS meta-analysis as published in Mahajan et al. (2014). For access to these, please follow the links to the left.

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