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Celldex Therapeutics

Celldex is developing targeted therapeutics to address devastating diseases for which available treatments are inadequate.

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Celldex Therapeutics | fiscalresponsibility.us Reviews
<META>
DESCRIPTION
Celldex is developing targeted therapeutics to address devastating diseases for which available treatments are inadequate.
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1 combination immunotherapy
2 triple negative breast cancer
3 Celldex Therapeutics
4 Celldex
5 glembatumumab vedotin
6 varlilumab
7 CLDX
8 immuno-oncology
9
10 coupons
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careers,overview,management,board of directors,scientific advisory board,business development,benefits,current opportunities,locations,pipeline,glembatumumab vedotin,varlilumab,science,publications,clinical trials,compassionate use,investors and media
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Celldex Therapeutics | fiscalresponsibility.us Reviews

https://fiscalresponsibility.us

Celldex is developing targeted therapeutics to address devastating diseases for which available treatments are inadequate.

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1

Overview | Clinical Trials | Celldex Therapeutics

http://www.fiscalresponsibility.us/clinical-trials/clinical-trials-overview.php

Financial and SEC Reports. Celldex’s investigational medicines are being studied in multiple clinical trials. In many cases, these clinical trials are targeted to specific patient populations with high unmet medical need whose diseases express specific markers including many underserved or completely un-served orphan indications. To view a listing of clinical trials open to patient enrollment that include Celldex investigational medicines, please visit clinicaltrials.gov. Financial and SEC Reports.

2

CDX-0158 | Pipeline | Celldex Therapeutics

http://www.fiscalresponsibility.us/pipeline/cdx-0158.php

Financial and SEC Reports. CDX-0158 - Monoclonal Antibody Targeting KIT in Tumor Cells and Mast Cells. In January 2017 demonstrate that KIT inhibition in certain immune cells with CDX-0158 enhances the activity of checkpoint blockade, providing additional opportunities for combination therapy. This mechanism may also be effective with other immunotherapies, in particular with our CD27 agonist, varlilumab. For more information on the CDX-0158 program, view recent scientific presentations and publications.

3

Board of Directors | About | Celldex Therapeutics

http://www.fiscalresponsibility.us/about/board-of-directors.php

Financial and SEC Reports. Herbert J. Conrad. Former President, Roche Pharmaceuticals US. George O. Elston. Chief Financial Officer, Juniper Pharmaceuticals. James J. Marino, J.D. Former Partner, Dechert LLP. Anthony S. Marucci. Founder, President, Chief Executive Officer and Director. Gerald McMahon, Ph.D. Former President and CEO, Kolltan Pharmaceuticals. Harry H. Penner, Jr., J.D., L.L.M. Chairman and CEO, Nascent Bioscience. Karen L. Shoos, J.D. Financial and SEC Reports.

4

Varlilumab | Pipeline | Celldex Therapeutics

http://www.fiscalresponsibility.us/pipeline/cdx-1127.php

Financial and SEC Reports. Varlilumab Monoclonal Antibody Targeting CD27. Some tumors (B or T cell derived malignancies) have high CD27 expression. Varlilumab can bind these tumor cells directly and activate immune cell killing through a mechanism known as Antibody Dependent Cellular Cytotoxicity (ADCC). Varlilumab binding to the tumor cells may also interfere with tumor cell growth by additional mechanisms. Study at the 2013 American Association of Cancer Research Annual Meeting.

5

Locations | About | Celldex Therapeutics

http://www.fiscalresponsibility.us/about/locations.php

Financial and SEC Reports. Contact Us and Office Locations. General Inquiries: info@celldextherapeutics.com. Scientific Inquiries: science@celldextherapeutics.com. Celldex has offices in Hampton, NJ (corporate and research), New Haven, CT (clinical and research), Fall River, MA (manufacturing) and Needham, MA (operations and research). 53 Frontage Road, Suite 220. Hampton, NJ 08827. T: (908) 454-7120; F: (908) 454-1911. Take Route 78 West to exit 12. Take a left at the end of the off-ramp. New Haven, CT.

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Celldex Therapeutics

Financial and SEC Reports. For Patients with Devastating Diseases. Our company is growing by leaps and bounds! Discover a new opportunity with. Celldex Therapeutics and find your place in the future of immunotherapy. Now Enrolling Phase 2 Clinical Trial of Glembatumumab. Vedotin in Metastatic Triple Negative Breast Cancer. Celldex Provides Corporate Update and Reports Full Year 2016 Results. March 14, 2017. Celldex Therapeutics Announces Appointment to Board of Directors. March 1, 2017. February 13, 2017.

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