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InterVivo Solutions

Translational Models. Transformative Research. Sage KO and Transgenic Rat. PXB Humanized Liver Mouse. PK Bridge Screening Studies. Durk MR, Fan J, Sun H, Yang Y, Pang H, Pang KS, de Lannoy IA. Vitamin D Receptor Activation Induces P-Glycoprotein and Increases Brain Efflux of Quinidine: An Intracerebral Microdialysis Study in Conscious Rats. Pharm Res. 2014 Oct 16. [Epub ahead of print]. Fan J, de Lannoy IA. Biochem Pharmacol. 2014 Jan 1;87(1):93-120. Review. Aimone LD1, de Lannoy IA. Evaluation of chemic...

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Translational Models. Transformative Research. Sage KO and Transgenic Rat. PXB Humanized Liver Mouse. PK Bridge Screening Studies. Durk MR, Fan J, Sun H, Yang Y, Pang H, Pang KS, de Lannoy IA. Vitamin D Receptor Activation Induces P-Glycoprotein and Increases Brain Efflux of Quinidine: An Intracerebral Microdialysis Study in Conscious Rats. Pharm Res. 2014 Oct 16. [Epub ahead of print]. Fan J, de Lannoy IA. Biochem Pharmacol. 2014 Jan 1;87(1):93-120. Review. Aimone LD1, de Lannoy IA. Evaluation of chemic...

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3 news

4 management

5 careers

6 efficacy

7 overview

8 pain and epilepsy

9 obesity and addiction

10 parkinson's disease

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InterVivo Solutions | intervivosolutions.com Reviews

https://intervivosolutions.com

Translational Models. Transformative Research. Sage KO and Transgenic Rat. PXB Humanized Liver Mouse. PK Bridge Screening Studies. Durk MR, Fan J, Sun H, Yang Y, Pang H, Pang KS, de Lannoy IA. Vitamin D Receptor Activation Induces P-Glycoprotein and Increases Brain Efflux of Quinidine: An Intracerebral Microdialysis Study in Conscious Rats. Pharm Res. 2014 Oct 16. [Epub ahead of print]. Fan J, de Lannoy IA. Biochem Pharmacol. 2014 Jan 1;87(1):93-120. Review. Aimone LD1, de Lannoy IA. Evaluation of chemic...

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intervivosolutions.com

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About Us

http://www.intervivosolutions.com/company/overview

Translational Models. Transformative Research. At InterVivo Solutions, our aim is to improve the clinical success of new drugs by providing translational models and transformative research services. We achieve this goal by providing:. Clinically relevant animal models of disease and drug disposition in multiple species. Access to state-of-the-art tools and techniques. Expertise in adding value to pre-clinical drug assets and drug discovery programs.

2

Overview

http://www.intervivosolutions.com/safety/overview

Translational Models. Transformative Research. Pharmacokinetics (PK) studies provide the basis for interpreting the dose-related efficacy, safety and toxicological effects of a New Chemical Entity. InterVivo's advanced surgical techniques and depth of PK expertise provides a unique combination of quality, reliability and value for sponsors throughout the drug development process. Firstly, to discover risks of an NCE at the earliest stage to enable informed financial and technical resource decisions. ...

3

Overview

http://www.intervivosolutions.com/imaging/overview

Translational Models. Transformative Research. The brain can be imaged in a variety of different ways, the choice of imaging modality depending on the research question being answered. Imaging modalities that can be utilized include MRI, CT, PET and SPECT. A variety of different quantitative measures can be provided including volumetric and functional data.

4

Alzheimer's Disease

http://www.intervivosolutions.com/efficacy/ad

Translational Models. Transformative Research. Memory loss is an early feature of the disease, which progresses to loss of cognitive ability, language, social function, and ultimately death. It is the most common cause of dementia and is becoming increasingly prevalent due to increases in longevity. Our most advanced model system is the aged dog which shows natural Alzheimer's like pathology.

5

Image Processing

http://www.intervivosolutions.com/imaging/image-processing

Translational Models. Transformative Research. Dog brain segmented into grey matter, white matter and cerebrospinal fluid. InterVivo Solutions has experience in image processing of all modalities. Image processing extracts quantitative data from images. This can range from basic morphometric measurements made from images such as bone length or hippocampal volume to complex segmentation based on image signal intensities. Dog brain segmented into grey matter.

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Translational Models. Transformative Research. Sage KO and Transgenic Rat. PXB Humanized Liver Mouse. PK Bridge Screening Studies. Durk MR, Fan J, Sun H, Yang Y, Pang H, Pang KS, de Lannoy IA. Vitamin D Receptor Activation Induces P-Glycoprotein and Increases Brain Efflux of Quinidine: An Intracerebral Microdialysis Study in Conscious Rats. Pharm Res. 2014 Oct 16. [Epub ahead of print]. Fan J, de Lannoy IA. Biochem Pharmacol. 2014 Jan 1;87(1):93-120. Review. Aimone LD1, de Lannoy IA. Evaluation of chemic...

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