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Tay-Sachs Disease | Lipid Storage DisorderLipid Storage Disorder
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Lipid Storage Disorder
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Problems with β-hexosaminidase A cause lipid buildup | Tay-Sachs Disease
https://maddyduplessis.wordpress.com/2014/03/14/biochemistry-of-the-disorder
March 14, 2014. Problems with β-hexosaminidase A cause lipid buildup. Tay Sachs is caused by abnormalities in the enzyme β-hexosaminidase A (Hex A). There are two subunits to this enzyme: the α-subunit encoded by. And the β-subunit encoded by. Pictured below. This is because of the negatively charged sialic acid residue. The polar head group consists of a complex oligosaccharide. The colored shapes. Represent the sugar residues; using a common scientific convention, the blue circle represents glucose, th...
The 80-year process of discovering Tay-Sachs | Tay-Sachs Disease
https://maddyduplessis.wordpress.com/2014/04/02/40
April 2, 2014. The 80-year process of discovering Tay-Sachs. The metabolic pathway affected by Tay – Sachs disease is the cyclic synthesis and breakdown of the GM1 ganglioside in the developing neural tissue. Although Tay – Sachs disease was characterized and named towards the end of the 19. The Structure of the GM1, GM2 and GM3 gangliosides. Okada and O’Brien (1969). 2), 101 106. doi:10.1016/0009-9120(95)00003-R. Okada, S., and O’Brien, J. S. (1969). Tay-Sachs disease: generalized absenc...3894), 698 700.
About | Tay-Sachs Disease
https://maddyduplessis.wordpress.com/about
This blog is a research project for BMB 320 – Cellular Metabolism. It focuses on Tay-Sachs Disease, a metabolic disorder of lipid storage. Leave a Reply Cancel reply. Enter your comment here. Fill in your details below or click an icon to log in:. Address never made public). You are commenting using your WordPress.com account. ( Log Out. You are commenting using your Twitter account. ( Log Out. You are commenting using your Facebook account. ( Log Out. Notify me of new comments via email.
March | 2014 | Tay-Sachs Disease
https://maddyduplessis.wordpress.com/2014/03
March 14, 2014. Problems with β-hexosaminidase A cause lipid buildup. Tay Sachs is caused by abnormalities in the enzyme β-hexosaminidase A (Hex A). There are two subunits to this enzyme: the α-subunit encoded by. And the β-subunit encoded by. Pictured below. This is because of the negatively charged sialic acid residue. The polar head group consists of a complex oligosaccharide. The colored shapes. Represent the sugar residues; using a common scientific convention, the blue circle represents glucose, th...
April | 2014 | Tay-Sachs Disease
https://maddyduplessis.wordpress.com/2014/04
April 14, 2014. Exciting Developments in Tay-Sachs Research. Screening companies are popping up. The genetic screening is typically done for. Mutations, the most common of which is an insertion of four nucleotides, TATC, in exon 11, causing a premature stopping point and subsequent instability of the. MRNA transcript. Almost 130 mutations in all have been characterized, but some researchers are continuing to try to find more. Mutations, because this couldlead to more effective and common screening. Clark...
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Tay-Sachs Disease | Lipid Storage Disorder
April 14, 2014. Exciting Developments in Tay-Sachs Research. Screening companies are popping up. The genetic screening is typically done for. Mutations, the most common of which is an insertion of four nucleotides, TATC, in exon 11, causing a premature stopping point and subsequent instability of the. MRNA transcript. Almost 130 mutations in all have been characterized, but some researchers are continuing to try to find more. Mutations, because this couldlead to more effective and common screening. Clark...
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