niessenlab.uni-koeln.de
Niessen LaboratoryOverall, we focus on three main research questions. How do cell adhesion and polarity pathways regulate barrier formation, self-renewal and homeostasis in a stratified epithelium? How do cell adhesion and polarity pathways couple to signal transduction pathways to regulate stem cell behavior, barrier function and tissue homeostasis? How do age-associated alterations in molecular regulators of cell architecture alter progenitor cell behavior and result in impairment of the skin barrier?
http://niessenlab.uni-koeln.de/