p53.iarc.fr
Welcome - IARC TP53 DatabaseIARC TP53 Database: knowledgebase and statistical tools for the analysis of TP53 gene mutations in human cancers
http://p53.iarc.fr/
IARC TP53 Database: knowledgebase and statistical tools for the analysis of TP53 gene mutations in human cancers
http://p53.iarc.fr/
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Welcome - IARC TP53 Database | p53.iarc.fr Reviews
https://p53.iarc.fr
IARC TP53 Database: knowledgebase and statistical tools for the analysis of TP53 gene mutations in human cancers
p53.iarc.fr
TP53 sequences
http://p53.iarc.fr/p53Sequences.aspx
Reference sequences used to annotate TP53 gene variations. The Genomic sequence, NC 000017.10. Is now used (since R17 version) as default for describing mutations at the genome level. Exon-intron boundaries for the main p53 isoform and polymorphic sites are shown here. Coding and protein sequence. With residue numbers, amino-acids, highlighted CpG sites and exon-intron boundaries. NCBI link to cDNA sequence. Corresponding to the NM 000546 isoform. Other links to human sequences. Gene view at ENSEMBL.
User's manual
http://p53.iarc.fr/Manual.aspx
Datasets and their annotations. Graphs and search options. The IARC TP53 database contains exclusively TP53 mutations associated with human cancers that have been identified by sequencing and published in the peer-reviewed literature or compiled in mutation data repositories. Data are organized in datasets that can be searched and analyzed. With graph tools (see below) or fully downloaded. Downloaded files, annotations and graph tools are described below. Page, do not hesitate to contact us at . For muta...
IARC TP53 Search
http://p53.iarc.fr/CellLines.aspx
Mutation conversion with: Mutalizer. Selected Statistics on Cell-Lines. For details on dataset contents and annotations, see the user manual. Please note that cell-line data are also included in the dataset od somatic mutations. Cell-Line Name and Tissue. ANUS[Carcinoma, NOS,Squamous cell carcinoma, NOS]. BONES (limbs)[Cancer, NOS,Chondroblastic osteosarcoma (C40. , C41. ),Chondrosarcoma, NOS (C40. , C41. ),Ewing sarcoma,Malignant fibrous histiocytoma,Neoplasm, benign,Osteosarcoma, NOS (C...CERVIX UTERI[...
p53 Structure analysis
http://p53.iarc.fr/StructureAnalysis.aspx
This page provides a tool to visualize the position of mutations in the 3D structure of the DNA-binding domain of p53 protein. Links to other p53 structures and structural properties of p53 and p53 mutants are also provided. View structural motifs of p53 DNA-binding domain in contact with DNA*: color residues (96 to 289) with options bellow (you may select several residues separated by a comma). You need to download and install JAVA. Plug-in to use this tool. Download structures and tools.
Disclaimer
http://p53.iarc.fr/Disclaimer.aspx
The IARC TP53 Database is a free service offered to the scientific community. When using the database, authors should cite the following publication:. Petitjean A, Mathe E, Kato S, Ishioka C, Tavtigian SV, Hainaut P, Olivier M. Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database. Hum Mutat. 2007 Jun;28(6):622-9. The version of the database should be identified (R18, April 2016 is the latest).
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TP53 - Genetics Home Reference
https://ghr.nlm.nih.gov/gene/TP53
Skip to main content. Your Guide to Understanding Genetic Conditions. Help Me Understand Genetics. Gene provides instructions for making a protein called tumor protein p53 (or p53). This protein acts as a tumor suppressor, which means that it regulates cell division by keeping cells from growing and dividing too fast or in an uncontrolled way. Because p53 is essential for regulating cell division and preventing tumor formation, it has been nicknamed the "guardian of the genome.". What is a gene? Gene gre...
Locus Specific Databases
http://www.sjtud.org/locus-specific-databases.html
Ultimate Database Entry / Retrieval Portal. IMPORTANT DATABASES / SITES.
Eupancreas
http://eupancreas.com/e-library
MEETINGS & EVENTS. Treatment and supportive care. Taking Part in Research Studies. Pathology and Genetics of Tumours of the Digestive System. EAPM Annual Conference Report. Featured Journal Issue: Molecular Carcinonesis 2012. Epidemiological and Etiological Mechanisms in Pancreatic Cancer. MD Anderson Solid Tumor Oncology Series: Pancreatic Cancer. Software and databases for pancreatic cancer researchy. GLOBOCAN 2012: Estimated Cancer Incidence, Mortality and Prevalence Worldwide in 2012. RARECARENet Inf...
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The TP53 Website - The TP53 Web Site
The TP53 Cell Line compendium. Mutant Loss Of Activity Database. TP53 : Recommended Guidelines. Welcome to the novel TP53 website. After 20 years of existence with more than 4 million pages visited, the old TP53 website ( http:/ p53.free/.fr). Has been closed and has been replaced by its successor ( p53.fr. Novel features and tools include the TP53 cell line compendium, a revised version of TP53 mutation assessor and the last issue of the UMD TP53 database. With more than 80,000. In a Post-Genomic Era.
p53.genetika.lt
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Welcome - IARC TP53 Database
The IARC TP53 Database compiles various types of data and information on human TP53 gene variations related to cancer. Data are compiled from the peer-reviewed literature and from generalist databases. See detailed information on database contents in the user's guide. 25 Years of p53 book. IARC, 150 Cours Albert Thomas, 69372 Lyon CEDEX 08, France - Tel: 33 (0)4 72 73 84 85 - Fax: 33 (0)4 72 73 85 75.
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