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Plenge Gen @rplenge - Discovery Research | Better HealthPlenge Gen @rplenge

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Plenge Gen @rplenge - Discovery Research | Better HealthPlenge Gen @rplenge | plengegen.com Reviews
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Discovery Research | Better Health
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2 blog
3 robert
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5 human genetics
6 precision medicine
7 embedded genomics
8 immunogenomics
9 drug discovery
10 navigate
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Plenge Gen @rplenge - Discovery Research | Better HealthPlenge Gen @rplenge | plengegen.com Reviews

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Discovery Research | Better Health

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1

Mendelian randomization for drug discovery and development: highlights from Bristol meeting (June 2015) | Plenge Gen @rplenge

https://www.plengegen.com/blog/mendelian-randomization-drug-discovery-development-highlights-bristol-meeting-june-2015

Mendelian randomization for drug discovery and development: highlights from Bristol meeting (June 2015). Date posted: June 26, 2015 Author: Robert Plenge. I attended the Mendelian randomization meeting. In Bristol, UK this past week (link to the program’s oral abstracts here. The meeting was timed with the release of a number of articles in the. International Journal of Epidemiology. Volume 44, No. 2 April 2015 TOC here. And how Mendelian randomization (MR) is applied within this framework. In partic...

2

Plenge Gen @rplenge - Page 2

https://www.plengegen.com/page/2

Articles of the week: IL23 and psoriasis, Mendelian randomization and IL1. Date posted: March 9, 2015 Author: Robert Plenge. My overly simplistic vision of the way to transform drug discovery is to (1). Pick targets based on causal human biology (e.g., experiments of nature, especially human genetics), (2). Develop drugs that recapitulate the biology of the human experiments of nature (e.g., therapeutic inhibitors of proteins), (3). Develop biomarkers that measure target modulation in humans, and (4).

3

My personal vision | Plenge Gen @rplenge

https://www.plengegen.com/vision

My personal mission is to perform discovery research that starts and ends with the patient. Message about my personal Vision:. While I have worked in academics and currently work at Merck, I always remember that the patient is my ultimate stakeholder. Everything I do in my professional career is to make the lives of patients better. I start with the simple yet profound questions that patients used to ask me when I practiced clinical medicine: “. Why did I develop this disease? 8221; “. 8221; “. Resilienc...

4

Genetic & Pharmacogenomic (GpGx) retreat: integrate and elevate | Plenge Gen @rplenge

https://www.plengegen.com/blog/genetic-pharmacogenomic-gpgx-retreat-integrate-elevate

Genetic & Pharmacogenomic (GpGx) retreat: integrate and elevate. Date posted: June 17, 2015 Author: Robert Plenge. We held our second annual GpGx retreat last week at the. Dolce Norwalk Conference Center. In Norwalk, CT. Integrate across Translational Medicine and elevate our mission to infuse cutting-edge genetics and genomics into Merck’s pipeline. What follows is a brief recount of the event. At the start of the retreat, I provided an overview on our theme:. This topic was chosen as (a). Manu emphasiz...

5

Personalized medicine vs precision medicine | Plenge Gen @rplenge

https://www.plengegen.com/blog/personalized-medicine-precision-medicine

Personalized medicine vs precision medicine. Date posted: March 16, 2013 Author: Robert Plenge. For our website, we have chosen the term “precision medicine” rather than “personalized medicine”. A recent News article in. Reinforces this concept (see here. I have had many of my non-genetic physician colleagues comment to me: “. We practice personalized medicine every day. It’s called basic patient care! Article emphasizes “. We already practice personalized medicine. 8221; are the first to admit “. Toward...

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The Multivalent Mathai Mammen – HUMAN PROOF OF CONCEPT

http://humanpoc.com/mathai-mammen

HUMAN PROOF OF CONCEPT. The Biotech Venture Capital Podcast. The Multivalent Mathai Mammen. In the late nineties, a company named “Advanced Medicine” came together with the 4Cs of entrepreneurship in place: a concept, co-founders, capital, and some well-placed cold-calls. Mathai Mammen was one of those co-founders, still living in a dorm at the time. The company’s investors evolved, it renamed itself, went public, and ultimately split into two independent companies: Innoviva. Podcast: Play in new window.

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Ron Cohen: Founder & Confounder (Part 2) – HUMAN PROOF OF CONCEPT

http://humanpoc.com/ron-cohen-2

HUMAN PROOF OF CONCEPT. The Biotech Venture Capital Podcast. Ron Cohen: Founder & Confounder (Part 2). This past year, Ron took over the role of Chair of BIO. This episode, Part 2 of the two-part interview, picks up where Part 1. Left off, on the subject of social media’s role in biotech. Podcast: Play in new window. Duration: 28:14 — 39.0MB). Introducing the New Podcast where VC meets Biotech. Ron Cohen: Founder & Confounder (Part 1) →. Leave a Reply Cancel reply. Your email address will not be published.

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Introducing the Podcast – HUMAN PROOF OF CONCEPT

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HUMAN PROOF OF CONCEPT. The Biotech Venture Capital Podcast. Every human needs medical treatment at some point. Yet the life sciences and venture capital industries the dual engines driving medical discoveries could scarcely be more specialized and exclusive. Human Proof of Concept. Is the podcast that demystifies the inner workings of venture-backed medical innovation, providing access and insights from the key players who shape the space. Human Proof of Concept. Press Pause for a Cause. Trio, used with...

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Introducing the New Podcast where VC meets Biotech – HUMAN PROOF OF CONCEPT

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HUMAN PROOF OF CONCEPT. The Biotech Venture Capital Podcast. Introducing the New Podcast where VC meets Biotech. Human Proof of Concept. The Biotech Venture Capital podcast hosted by Janelle R. Anderson. Podcast: Play in new window. Duration: 1:11 — 1.9MB). Ron Cohen: Founder & Confounder (Part 2) →. Leave a Reply Cancel reply. Your email address will not be published. Required fields are marked *. Press Pause for a Cause. Human Proof of Concept. Is - and will always be - available for free.

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Janelle R. Anderson – HUMAN PROOF OF CONCEPT

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HUMAN PROOF OF CONCEPT. The Biotech Venture Capital Podcast. Janelle R. Anderson. Janelle is currently a Managing Partner at CTI Life Sciences Fund. Thanks to quantum mechanics, she is often simultaneously in two states (New York and Massachusetts). Janelle has attained a white belt in taekwondo and is a former professional steel drum player. She speaks french – poorly. Press Pause for a Cause. Human Proof of Concept. Is - and will always be - available for free. To learn more and donate. Don’t Mis...

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Glen de Vries has his Head in the Cloud – HUMAN PROOF OF CONCEPT

http://humanpoc.com/glen-devries

HUMAN PROOF OF CONCEPT. The Biotech Venture Capital Podcast. Glen de Vries has his Head in the Cloud. In 1999 Glen de Vries started a tech company in his 5th floor walkup – very much the NYC equivalent of a garage in Silicon Valley. Today Medidata Solutions. Continues to transform human drug studies with their clinical cloud platform. They are approaching 3M patients and a $3B market cap. Glen explains how he plans to reach escape velocity with no exit strategy. Podcast: Play in new window. Trio, used wi...

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Barry Kappel and Gerard Honig – Live! – HUMAN PROOF OF CONCEPT

http://humanpoc.com/barry-kappel-gerard-honig

HUMAN PROOF OF CONCEPT. The Biotech Venture Capital Podcast. Barry Kappel and Gerard Honig – Live! Barry Kappel of Sapience Therapeutics. And Gerard Honig of Symbiotic Health. Joined me for a fireside chat at the Foundation2016. Held at Cold Spring Harbor Labs, it was a beautiful day in pre-election times. If you listen closely you can hear local wildlife in the background: birds chirping and (the) James Watson roaring around campus in his Porsche. Podcast: Play in new window. Leave a Reply Cancel reply.

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Kate Bingham, a Voice of Reason from the UK – HUMAN PROOF OF CONCEPT

http://humanpoc.com/kate-bingham

HUMAN PROOF OF CONCEPT. The Biotech Venture Capital Podcast. Kate Bingham, a Voice of Reason from the UK. Brexit isn’t the only newsworthy and dismal problem out there. Consider a couple of others – some VCs would rather not touch them with a ten foot pole, yet Kate Bingham is taking a stab at them:. There’s Alzheimers. This past October, SV Life Sciences. Where she is Managing Partner, became the fund manager of the Dementia Discovery Fund. Launched with a charity. Podcast: Play in new window. Press Pau...

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Daily Digestif featuring Martin Lehr – HUMAN PROOF OF CONCEPT

http://humanpoc.com/martin-lehr

HUMAN PROOF OF CONCEPT. The Biotech Venture Capital Podcast. Daily Digestif featuring Martin Lehr. After a run-in with Joe Biden’s entourage, Marty Lehr joined me on the first full day of the 35th Annual J.P. Morgan Healthcare Conference. He discussed his prior life at Osage University Partners. His current life at Context Therapeutics. And how his romantic life once dictated his professional life. Podcast: Play in new window. Duration: 15:43 — 21.8MB). Glen de Vries has his Head in the Cloud. The statem...

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Stéphane Bancel: The Messenger is the Medium – HUMAN PROOF OF CONCEPT

http://humanpoc.com/stephane-bancel

HUMAN PROOF OF CONCEPT. The Biotech Venture Capital Podcast. Stéphane Bancel: The Messenger is the Medium. Is the Kendall Square startup developing a variety of drugs made of messenger RNA, leaving your cells to translate them into proteins. Forging a new ecosystem doesn’t come cheap: in only 5 years, Moderna has raised nearly $2B and is valued around $5B. And has even moved up in the ranks. What is going on over there? Podcast: Play in new window. Duration: 34:21 — 47.4MB). Leave a Reply Cancel reply.

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On Line. Here you can find examples of the best pictures of this renowned Peruvian photographer. The site is in development and soon more images will be made available on-line. We have the most complete Photo Archives. Of Peru in the business, focussing on Nature, Wildlife, Ancient Cultures and the Peruvian People. Especially well represented are: the Amazon Rainforest. Also you can find our interesting Photo Stories. Our staff will be pleased to help you find the right images. Contact us.

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Plenge GmbH | Ihr Spezialist für Elektrotechnik und Steuerungsbau

Bietet Ihnen maßgeschneiderte Komplettlösungen. Lanen – P. Roduzieren – P. Der Schaltschrank ist das Herz Ihrer Anlage. Der Schaltschrank ist aber auch Kern unseres Unternehmens und Fokus unseres Teams. Er durchläuft die. Um Ihren Anlagen Leben einzuhauchen, unterstützt Sie Team Plenge mit innovativen Lösungen und der technischen Kompetenz eines erfahrenen Schaltschrankbauers. Dies gilt von der Planung bis hin zur Programmierung. Unsere Planung beinhaltet Hardware-. 5 Jan, 2017. Die Plenge GmbH begrüßt H...

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En vidunderlig dag på havet, grill og solnedgang på Ven - Michael Thomsen / Webasto. Gennem mange års erfaring i planlægning og afvikling af større og mindre arrangementer i ind- og udland, har jeg givet stadig flere virksomheder oplevelser lidt udover det sædvanlige, og med stort udbytte. Sejlads, Yacht, Lerdueskydning, Masterchef. Porsche Experience, Dubai, Sydfrankrig. Møder, Konferencer, Kick-off, Hotel. Djævleræs, Team Driving Challenge. Kristoffer Nielsen - Rynkeby. Tlf 20 310 007.

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Plenge Gen @rplenge - Discovery Research | Better HealthPlenge Gen @rplenge

NASH, HSD17B13 and era of programmable therapeutics. Date posted: April 13, 2018 Author: Robert Plenge. Disclaimer: I am an employee of Celgene. The views reported here are my own. One potential solution is to use human genetics to pick targets, understand molecular mechanism, select pharmacodynamics biomarkers, and identify patients most likely to respond to treatment (see. While intuitively appealing and supported by retrospective analyses ( here. It were possible to select an off-the shelf therapeutic...

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Laboratorio Plenge | C. H. Plenge & Cía. S.A.

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Willkommen

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Denne blog indeholder overvejelser og eftertanker om professionelle samtaler og konfliktløsning. Bloggen er knyttet til www.plengenet.dk. Torsdag den 24. april 2014. SIDSTE DAGLIGSTUEKURSUS FØR SOMMEREN 18. juni om effektive møder. Dagligstuekurser for små grupper i foråret 2014. Saml en håndfuld kolleger eller kig bare selv ind i min stue på Islands Brygge. Det er ikke længere muligt at booke til de to første dage. Mandag den 19. maj, 16.30 - 18.30. Hvad er konfliktmægling - og hvordan foregår det?

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