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CONTACTS AT RADICALTHERAPEUTIX.COM

Radical Therapeutix, Inc.

Roberta Gottlieb

3902 St●●●●●●●ge Lane

Ranch●●●●●ta Fe , CA, 92091

US

1.85●●●●1220
ro●●●●●@sciences.sdsu.edu

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Radical Therapeutix, Inc.

Roberta Gottlieb

3902 St●●●●●●●ge Lane

Ranch●●●●●ta Fe , CA, 92091

US

1.85●●●●1220
ro●●●●●@sciences.sdsu.edu

View this contact

Radical Therapeutix, Inc.

Roberta Gottlieb

3902 St●●●●●●●ge Lane

Ranch●●●●●ta Fe , CA, 92091

US

1.85●●●●1220
ro●●●●●@sciences.sdsu.edu

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Radical Therapeutix | Science

http://www.radicaltherapeutix.com/science.html

Small Molecules for Big Problems. By screening FDA-approved drugs for their ability to modulate autophagy,we have identified multiple cardioprotective agents, and we have compelling preclinical data in rodents and swine. These drugs, which can greatly reduce ischemic damage,could have a profound benefit to patients experiencing a heart attack by decreasing the risk of heart failure, a common consequence of a heart attack. MODULATING AUTOPHAGY TO SAVE THE HEART. NEW APPROACHES TO PROTECTING THE HEART.

2

Radical Therapeutix | Resources

http://www.radicaltherapeutix.com/resources.html

Small Molecules for Big Problems. A strong scientific foundation underlies Radical Therapeutix's strategy and processes. A selected list of references is provided below:. Autophagy and protein kinase C are required for cardioprotection by sulfaphenazole. American Journal Physiolology Heart Circ Physiol. Volume 298 Issue 2 February 2010, pages 570-9. Link: http:/ ajpheart.physiology. Recycle or die: The role of autophagy in cardioprotection. Asa B Gustafsson, Roberta A. Gottlieb.

3

Radical Therapeutix | Investors

http://www.radicaltherapeutix.com/investors.html

Small Molecules for Big Problems. Radical Therapeutix, Inc. is currently seeking angel and/or Venture support to build a successful cardiotherapeutic company. Current intellectual property held is summarized below. Financial information will be shared with potential serious investors. We welcome all calls/inquiries involving financing. You can find our contact information in the About Us.

4

Radical Therapeutix | About Us

http://www.radicaltherapeutix.com/aboutus.html

Small Molecules for Big Problems. Dr Wentworth is a Professor of Chemistry at The Scripps Research Institute and Professor of Medicinal Chemistry and Director of The Scripps-Oxford Laboratory, Department of Biochemistry, University of Oxford. Dr Wentworth’s interests include cholesterol ozonolysis products and their role in ischemia/reperfusion, atherosclerosis and Alzheimer’s disease, and development of novel therapeutics for the parasite Leishmania. Paul Wentworth, Jr., Ph.D. Research to date has been ...

5

Radical Therapeutix | Home

http://www.radicaltherapeutix.com/index.html

Small Molecules for Big Problems. Radical Therapeutix, Inc., is a drug discovery company developing small molecule therapeutics to treat. Diseases and pathologic conditions associated with tissue inflammation, ischemia and reperfusion injury, exemplified by. Acute myocardial infarction (AMI). In animal models of myocardial infarction, t. Agents are unique in that they can reduce the extent of tissue damage even when given at reperfusion,. In studies funded by NIH, we have characterized a number of. We ha...

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Small Molecules for Big Problems. Radical Therapeutix, Inc., is a drug discovery company developing small molecule therapeutics to treat. Diseases and pathologic conditions associated with tissue inflammation, ischemia and reperfusion injury, exemplified by. Acute myocardial infarction (AMI). In animal models of myocardial infarction, t. Agents are unique in that they can reduce the extent of tissue damage even when given at reperfusion,. In studies funded by NIH, we have characterized a number of. We ha...

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