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Ribosomal Proteins

The nucleolus is a dynamic structure whose morphology informs us on the health status of a cell. It is a long-known cancer biomarker and a recently demonstrated therapeutic target. It is therefore important to understand how it is organized structurally and maintained. Ribosomal proteins (r-proteins) control the expression and activity of key tumor suppressors, and they are mutated in multiple cancer predisposition disorders known as ribosomopathies. 8211; Nucleolar Structure. 8211; Mature rRNA.

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Ribosomal Proteins | riboprot.ulb.ac.be Reviews

<META> DESCRIPTION

The nucleolus is a dynamic structure whose morphology informs us on the health status of a cell. It is a long-known cancer biomarker and a recently demonstrated therapeutic target. It is therefore important to understand how it is organized structurally and maintained. Ribosomal proteins (r-proteins) control the expression and activity of key tumor suppressors, and they are mutated in multiple cancer predisposition disorders known as ribosomopathies. 8211; Nucleolar Structure. 8211; Mature rRNA.

<META> KEYWORDS

1 results overview

2 nucleolar structure

3 mature rrna accumulation

4 pre rrna processing

5 p53 steady state level

6 individual datasheet

7 small subunit

8 new nomenclature

9 old nomenclature

10 us2 rpsa

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results overview,nucleolar structure,mature rrna accumulation,pre rrna processing,p53 steady state level,individual datasheet,small subunit,new nomenclature,old nomenclature,us2 rpsa,rack1 rack1,rpsa,large subunit,rationale,methods,stats,faqs,belgium

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Ribosomal Proteins | riboprot.ulb.ac.be Reviews

https://riboprot.ulb.ac.be

The nucleolus is a dynamic structure whose morphology informs us on the health status of a cell. It is a long-known cancer biomarker and a recently demonstrated therapeutic target. It is therefore important to understand how it is organized structurally and maintained. Ribosomal proteins (r-proteins) control the expression and activity of key tumor suppressors, and they are mutated in multiple cancer predisposition disorders known as ribosomopathies. 8211; Nucleolar Structure. 8211; Mature rRNA.

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riboprot.ulb.ac.be

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METHODS – p53 Steady-State Level | Ribosomal Proteins

http://riboprot.ulb.ac.be/methods-stats/steady-state-level

METHODS – p53 Steady-State Level. Legend : METHODS – p53 Steady-State Level. 8211; Nucleolar Structure. 8211; Mature rRNA. 8211; pre-rRNA Processing. 8211; p53 Steady-State Level. Université Libre de Bruxelles. Rue Profs Jeener and Brachet, 12.

2

Mature rRNA Accumulation | Ribosomal Proteins

http://riboprot.ulb.ac.be/results-overview/mature-rrna-accumulation

Legend : Mature rRNA Accumulation. 28S/18S ratio calculated from agilent bioanalyzer electropherograms. Data shown for two distinct siRNAs used. 8211; Nucleolar Structure. 8211; Mature rRNA. 8211; pre-rRNA Processing. 8211; p53 Steady-State Level. Université Libre de Bruxelles. Rue Profs Jeener and Brachet, 12.

3

FAQS | Ribosomal Proteins

http://riboprot.ulb.ac.be/faqs

8211; Nucleolar Structure. 8211; Mature rRNA. 8211; pre-rRNA Processing. 8211; p53 Steady-State Level. Université Libre de Bruxelles. Rue Profs Jeener and Brachet, 12.

4

p53 Steady-State Level | Ribosomal Proteins

http://riboprot.ulb.ac.be/results-overview/steady-state-level

Legend : P53 Steady-State Level. The histogram shows r-proteins classified according to their impact on p53 steady-state accumulation. The nontargeting (Scr) control is shown in red, the RPS in green, and the RPL in magenta. The histogram bars are the means of triplicates with SD indicated. R-proteins whose depletion leads to a 5-fold increase in p53 levels are highlighted in a shaded box. 8211; Nucleolar Structure. 8211; Mature rRNA. 8211; pre-rRNA Processing. 8211; p53 Steady-State Level.

5

METHODS – Nucleolar Structure | Ribosomal Proteins

http://riboprot.ulb.ac.be/methods-stats/nucleolar-structure

METHODS – Nucleolar Structure. Legend : METHODS – Nucleolar Structure. 8211; Nucleolar Structure. 8211; Mature rRNA. 8211; pre-rRNA Processing. 8211; p53 Steady-State Level. Université Libre de Bruxelles. Rue Profs Jeener and Brachet, 12.

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ribosomalproteins.com

eS12 | Ribosomal Proteins

http://www.ribosomalproteins.com/eS12

Effect of r-protein depletions on pre-rRNA processing and mature rRNA accumulation: northern blots and ethidium bromide-stained denaturing agarose gels showing all RNA intermediates and mature rRNAs detected. The 28S/18S rRNA ratio was calculated from electropherograms. A calibration set (MOCK, SCR, UTP18 and NOL9) is included for reference. Schematics representing the RNAs detected are shown to the left. 8211; Nucleolar Structure. 8211; Mature rRNA. 8211; pre-rRNA Processing. 8211; p53 Steady-State Level.

ribosomalproteins.com

uS14 | Ribosomal Proteins

http://www.ribosomalproteins.com/uS14

Effect of r-protein depletions on pre-rRNA processing and mature rRNA accumulation: northern blots and ethidium bromide-stained denaturing agarose gels showing all RNA intermediates and mature rRNAs detected. The 28S/18S rRNA ratio was calculated from electropherograms. A calibration set (MOCK, SCR, UTP18 and NOL9) is included for reference. Schematics representing the RNAs detected are shown to the left. 8211; Nucleolar Structure. 8211; Mature rRNA. 8211; pre-rRNA Processing. 8211; p53 Steady-State Level.

ribosomalproteins.com

uS9 | Ribosomal Proteins

http://www.ribosomalproteins.com/uS9

Effect of r-protein depletions on pre-rRNA processing and mature rRNA accumulation: northern blots and ethidium bromide-stained denaturing agarose gels showing all RNA intermediates and mature rRNAs detected. The 28S/18S rRNA ratio was calculated from electropherograms. A calibration set (MOCK, SCR, UTP18 and NOL9) is included for reference. Schematics representing the RNAs detected are shown to the left. 8211; Nucleolar Structure. 8211; Mature rRNA. 8211; pre-rRNA Processing. 8211; p53 Steady-State Level.

ribosomalproteins.com

uS11 | Ribosomal Proteins

http://www.ribosomalproteins.com/uS11

Effect of r-protein depletions on pre-rRNA processing and mature rRNA accumulation: northern blots and ethidium bromide-stained denaturing agarose gels showing all RNA intermediates and mature rRNAs detected. The 28S/18S rRNA ratio was calculated from electropherograms. A calibration set (MOCK, SCR, UTP18 and NOL9) is included for reference. Schematics representing the RNAs detected are shown to the left. 8211; Nucleolar Structure. 8211; Mature rRNA. 8211; pre-rRNA Processing. 8211; p53 Steady-State Level.

ribosomalproteins.com

eS10 | Ribosomal Proteins

http://www.ribosomalproteins.com/eS10

Effect of r-protein depletions on pre-rRNA processing and mature rRNA accumulation: northern blots and ethidium bromide-stained denaturing agarose gels showing all RNA intermediates and mature rRNAs detected. The 28S/18S rRNA ratio was calculated from electropherograms. A calibration set (MOCK, SCR, UTP18 and NOL9) is included for reference. Schematics representing the RNAs detected are shown to the left. 8211; Nucleolar Structure. 8211; Mature rRNA. 8211; pre-rRNA Processing. 8211; p53 Steady-State Level.

ribosomalproteins.com

uS5 | Ribosomal Proteins

http://www.ribosomalproteins.com/uS5

Effect of r-protein depletions on pre-rRNA processing and mature rRNA accumulation: northern blots and ethidium bromide-stained denaturing agarose gels showing all RNA intermediates and mature rRNAs detected. The 28S/18S rRNA ratio was calculated from electropherograms. A calibration set (MOCK, SCR, UTP18 and NOL9) is included for reference. Schematics representing the RNAs detected are shown to the left. 8211; Nucleolar Structure. 8211; Mature rRNA. 8211; pre-rRNA Processing. 8211; p53 Steady-State Level.

ribosomalproteins.com

uS7 | Ribosomal Proteins

http://www.ribosomalproteins.com/uS7

Effect of r-protein depletions on pre-rRNA processing and mature rRNA accumulation: northern blots and ethidium bromide-stained denaturing agarose gels showing all RNA intermediates and mature rRNAs detected. The 28S/18S rRNA ratio was calculated from electropherograms. A calibration set (MOCK, SCR, UTP18 and NOL9) is included for reference. Schematics representing the RNAs detected are shown to the left. 8211; Nucleolar Structure. 8211; Mature rRNA. 8211; pre-rRNA Processing. 8211; p53 Steady-State Level.

ribosomalproteins.com

uS2 | Ribosomal Proteins

http://www.ribosomalproteins.com/uS2

Effect of r-protein depletions on pre-rRNA processing and mature rRNA accumulation: northern blots and ethidium bromide-stained denaturing agarose gels showing all RNA intermediates and mature rRNAs detected. The 28S/18S rRNA ratio was calculated from electropherograms. A calibration set (MOCK, SCR, UTP18 and NOL9) is included for reference. Schematics representing the RNAs detected are shown to the left. 8211; Nucleolar Structure. 8211; Mature rRNA. 8211; pre-rRNA Processing. 8211; p53 Steady-State Level.

ribosomalproteins.com

eS4 | Ribosomal Proteins

http://www.ribosomalproteins.com/eS4

Effect of r-protein depletions on pre-rRNA processing and mature rRNA accumulation: northern blots and ethidium bromide-stained denaturing agarose gels showing all RNA intermediates and mature rRNAs detected. The 28S/18S rRNA ratio was calculated from electropherograms. A calibration set (MOCK, SCR, UTP18 and NOL9) is included for reference. Schematics representing the RNAs detected are shown to the left. 8211; Nucleolar Structure. 8211; Mature rRNA. 8211; pre-rRNA Processing. 8211; p53 Steady-State Level.

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The nucleolus is a dynamic structure whose morphology informs us on the health status of a cell. It is a long-known cancer biomarker and a recently demonstrated therapeutic target. It is therefore important to understand how it is organized structurally and maintained. Ribosomal proteins (r-proteins) control the expression and activity of key tumor suppressors, and they are mutated in multiple cancer predisposition disorders known as ribosomopathies. 8211; Nucleolar Structure. 8211; Mature rRNA.

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