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Biomodels | Contract Research Services for Pre-Clinical Drug Development

Biomodels: Contract Research Services for Pre-Clinical Drug Development

http://staging.biomodels.com/

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Biomodels | Contract Research Services for Pre-Clinical Drug Development | staging.biomodels.com Reviews
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Biomodels: Contract Research Services for Pre-Clinical Drug Development
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2 Contract Research Services for Pre-Clinical Drug Development
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biomodels,about us,the biomodels advantage,professional profiles,history,capabilities,client testimonials,animal models,cancer supportive care,cachexia,oral mucositis,treatment related fatigue,dermatitis,myelosuppression,proctitis,osteonecrosis,arthritis
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Biomodels | Contract Research Services for Pre-Clinical Drug Development | staging.biomodels.com Reviews

https://staging.biomodels.com

Biomodels: Contract Research Services for Pre-Clinical Drug Development

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1

Cancer Supportive Care | Biomodels

http://staging.biomodels.com/animal-models/cancer-supportive-care

Colitis/Inflammatory Bowel Disease (IBD). Graft vs. Host Disease (GVHD). Head and Neck Cancer. Gastrointestinal Acute Radiation Syndrome (GI-ARS). Diabetes & Diabetic Wound Healing. Neurological and Psychological Disorders. Biomodels has become a leader in Cancer Supportive Care through its expertise in developing innovative models based on an understanding of the toxicity associated with chemotherapy and radiotherapy in the treatment of carcinomas. 313 Pleasant St.,. Watertown, MA 02472.

2

Osteonecrosis | Biomodels

http://staging.biomodels.com/animal-models/cancer-supportive-care/osteonecrosis

Colitis/Inflammatory Bowel Disease (IBD). Graft vs. Host Disease (GVHD). Head and Neck Cancer. Gastrointestinal Acute Radiation Syndrome (GI-ARS). Diabetes & Diabetic Wound Healing. Neurological and Psychological Disorders. Osteonecrosis of the Jaw (ONJ). Rats are treated with zoledronic acid and dexamethasone prior to dental extractions resulting in ONJ like changes. Up to 49 days. Osteonecrosis score, x-ray densitometry, histology. Osteonecrosis of the Jaw (ONJ). Watkins BA, Lyng GD. Watertown, MA 02472.

3

Sepsis | Biomodels

http://staging.biomodels.com/animal-models/inflammatory-diseases/sepsis

Colitis/Inflammatory Bowel Disease (IBD). Graft vs. Host Disease (GVHD). Head and Neck Cancer. Gastrointestinal Acute Radiation Syndrome (GI-ARS). Diabetes & Diabetic Wound Healing. Neurological and Psychological Disorders. Colitis/Inflammatory Bowel Disease (IBD). Graft vs. Host Disease (GVHD). LPS administration resulting in elevated cytokines. The LD50, LD75, or LD100 dose of LPS is administered and survival examined. 5 – 7 Days. Survival, Weight change. Serum TNF – a. In severe cases, sepsis can be a...

4

Oral Mucositis | Biomodels

http://staging.biomodels.com/animal-models/cancer-supportive-care/oral-mucositis-2

Colitis/Inflammatory Bowel Disease (IBD). Graft vs. Host Disease (GVHD). Head and Neck Cancer. Gastrointestinal Acute Radiation Syndrome (GI-ARS). Diabetes & Diabetic Wound Healing. Neurological and Psychological Disorders. Acute radiation model in hamsters. The Cheek pouch is treated with an acute dose of 40 Gy radiation resulting in the formation of ulcers. Mucositis score, histology. Fractionated radiation model in hamsters. Up to 36 days. Mucositis score, histology. Up to 36 days. Cheek pouch with ul...

5

The Biomodels Advantage | Biomodels

http://staging.biomodels.com/about/the-biomodels-advantage

Colitis/Inflammatory Bowel Disease (IBD). Graft vs. Host Disease (GVHD). Head and Neck Cancer. Gastrointestinal Acute Radiation Syndrome (GI-ARS). Diabetes & Diabetic Wound Healing. Neurological and Psychological Disorders. Fast Innovative. Predictive. Biomodels has earned accreditation from the Association for Assessment and Accreditation of Laboratory Animal Care International (AAALAC) for upholding the highest standards in animal use and care. 313 Pleasant St.,. Watertown, MA 02472.

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Graft vs. Host Disease (GVHD) | Biomodels

http://www.biomodels.com/animal-models/inflammatory-diseases/graft-vs-host-disease

Colitis/Inflammatory Bowel Disease (IBD). Graft vs. Host Disease (GVHD). Head and Neck Cancer. Gastrointestinal Acute Radiation Syndrome (GI-ARS). Diabetes & Diabetic Wound Healing. Neurological and Psychological Disorders. Graft vs. Host Disease (GVHD). Colitis/Inflammatory Bowel Disease (IBD). Graft vs. Host Disease (GVHD). Graft vs. Host Disease (GVHD). Development of GVHD is dependent on the activation of antigen-specific donor T cells that are able to mount a specific immune response targeting host ...

biomodels.com biomodels.com

Cancer Supportive Care | Biomodels

http://www.biomodels.com/animal-models/cancer-supportive-care

Colitis/Inflammatory Bowel Disease (IBD). Graft vs. Host Disease (GVHD). Head and Neck Cancer. Gastrointestinal Acute Radiation Syndrome (GI-ARS). Diabetes & Diabetic Wound Healing. Neurological and Psychological Disorders. Biomodels has become a leader in Cancer Supportive Care through its expertise in developing innovative models based on an understanding of the toxicity associated with chemotherapy and radiotherapy in the treatment of carcinomas. 313 Pleasant St.,. Watertown, MA 02472.

biomodels.com biomodels.com

Cachexia | Biomodels

http://www.biomodels.com/animal-models/cancer-supportive-care/cachexia

Colitis/Inflammatory Bowel Disease (IBD). Graft vs. Host Disease (GVHD). Head and Neck Cancer. Gastrointestinal Acute Radiation Syndrome (GI-ARS). Diabetes & Diabetic Wound Healing. Neurological and Psychological Disorders. Treatment with either a single cycle or two cycles of doxorubicin. Mean Percent Body Weight Change. Percent body weight change as a result of two cycles of doxorubicin treatment (days 1-3 and 10-12). 313 Pleasant St.,. Watertown, MA 02472.

biomodels.com biomodels.com

Multiple Sclerosis/EAE | Biomodels

http://www.biomodels.com/animal-models/inflammatory-diseases/multiple-sclerosiseae

Colitis/Inflammatory Bowel Disease (IBD). Graft vs. Host Disease (GVHD). Head and Neck Cancer. Gastrointestinal Acute Radiation Syndrome (GI-ARS). Diabetes & Diabetic Wound Healing. Neurological and Psychological Disorders. Colitis/Inflammatory Bowel Disease (IBD). Graft vs. Host Disease (GVHD). Myelin oligodendrocyte glycoprotein (MOG) is administered resulting in loss of muscletone. EAE score, histology. Proteolipid protein (PLP) is administered resulting in relapsing EAE symptoms. EAE score, histology.

biomodels.com biomodels.com

Dermatitis | Biomodels

http://www.biomodels.com/animal-models/cancer-supportive-care/dermatitis

Colitis/Inflammatory Bowel Disease (IBD). Graft vs. Host Disease (GVHD). Head and Neck Cancer. Gastrointestinal Acute Radiation Syndrome (GI-ARS). Diabetes & Diabetic Wound Healing. Neurological and Psychological Disorders. Acute Radiation Induced Dermatitis. Disease peaks at or around Day 12 with desquamation of approximately 50% of the irradiated area. Up to 36 days. Dermatitis score, histology. Fractionated Radiation Induced Dermatitis. Up to 36 days. Dermatitis score, histology. Animals receive one a...

biomodels.com biomodels.com

Inflammatory Diseases | Biomodels

http://www.biomodels.com/animal-models/inflammatory-diseases

Colitis/Inflammatory Bowel Disease (IBD). Graft vs. Host Disease (GVHD). Head and Neck Cancer. Gastrointestinal Acute Radiation Syndrome (GI-ARS). Diabetes & Diabetic Wound Healing. Neurological and Psychological Disorders. Colitis/Inflammatory Bowel Disease (IBD). Graft vs. Host Disease (GVHD). Biomodels interest in inflammatory disease stems from our interest in oral mucositis, and other complications of cancer therapy that involve the immune system. We offer models of antigen induced autoimmune di...

biomodels.com biomodels.com

Fibrosis | Biomodels

http://www.biomodels.com/animal-models/fibrosis

Colitis/Inflammatory Bowel Disease (IBD). Graft vs. Host Disease (GVHD). Head and Neck Cancer. Gastrointestinal Acute Radiation Syndrome (GI-ARS). Diabetes & Diabetic Wound Healing. Neurological and Psychological Disorders. 313 Pleasant St.,. Watertown, MA 02472.

biomodels.com biomodels.com

Pulmonary Fibrosis | Biomodels

http://www.biomodels.com/animal-models/fibrosis/pulmonary-fibrosis

Colitis/Inflammatory Bowel Disease (IBD). Graft vs. Host Disease (GVHD). Head and Neck Cancer. Gastrointestinal Acute Radiation Syndrome (GI-ARS). Diabetes & Diabetic Wound Healing. Neurological and Psychological Disorders. Intratracheal bleomycin-induced pulmonary fibrosis. Bleomycin introduced directly to lungs via cannula. Weight and respiratory status; weight, collagen content, and fibrosis score of lungs. Intravenous bleomycin-induced pulmonary fibrosis. Bleomycin introduced intravenously for 5 days.

biomodels.com biomodels.com

Osteonecrosis | Biomodels

http://www.biomodels.com/animal-models/cancer-supportive-care/osteonecrosis

Colitis/Inflammatory Bowel Disease (IBD). Graft vs. Host Disease (GVHD). Head and Neck Cancer. Gastrointestinal Acute Radiation Syndrome (GI-ARS). Diabetes & Diabetic Wound Healing. Neurological and Psychological Disorders. Osteonecrosis of the Jaw (ONJ). Rats are treated with zoledronic acid and dexamethasone prior to dental extractions resulting in ONJ like changes. Up to 49 days. Osteonecrosis score, x-ray densitometry, histology. Osteonecrosis of the Jaw (ONJ). Watkins BA, Lyng GD. Watertown, MA 02472.

biomodels.com biomodels.com

Proctitis | Biomodels

http://www.biomodels.com/animal-models/cancer-supportive-care/proctitis

Colitis/Inflammatory Bowel Disease (IBD). Graft vs. Host Disease (GVHD). Head and Neck Cancer. Gastrointestinal Acute Radiation Syndrome (GI-ARS). Diabetes & Diabetic Wound Healing. Neurological and Psychological Disorders. Acute Radiation- Induced Proctitis. Disease is evident at day 3, peaks near day 7 and persists through the final evaluation. Endoscopy score, weight, incidence of diarrhea, histology. Fractionated Radiation- Induced Proctitis. Endoscopy, score, weight, incidence of diarrhea, histology.

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Biomodels | Contract Research Services for Pre-Clinical Drug Development

Colitis/Inflammatory Bowel Disease (IBD). Graft vs. Host Disease (GVHD). Head and Neck Cancer. Gastrointestinal Acute Radiation Syndrome (GI-ARS). Diabetes & Diabetic Wound Healing. Neurological and Psychological Disorders. Learn More About the Biomodels Advantage. Upcoming Event August 8-12, 2015. World Congress on Inflammation. Previous Webinar June 25, 2015. Predictive Preclinical Animal Models of Pulmonary Disease. Previous Webinar May 28, 2015. 313 Pleasant St.,. Watertown, MA 02472.

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