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Twisted Bacteria

Aug 13, 2012. Keeping harmful protein fibres at bay. Misfolded proteins are not just useless — they can be toxic. Some of them form linear aggregates known as amyloid fibres. That can lead to disorders such as Alzheimer’s and Parkinson’s diseases. Writing in PLoS Biology. And colleagues describe a protein machinery that inhibits the formation and helps to dissolve such fibres. Reference (and source of the image):. DOI: 10.1371/journal.pbio.1001346. Read the rest of the article. Posted by César Sánchez.

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Aug 13, 2012. Keeping harmful protein fibres at bay. Misfolded proteins are not just useless — they can be toxic. Some of them form linear aggregates known as amyloid fibres. That can lead to disorders such as Alzheimer’s and Parkinson’s diseases. Writing in PLoS Biology. And colleagues describe a protein machinery that inhibits the formation and helps to dissolve such fibres. Reference (and source of the image):. DOI: 10.1371/journal.pbio.1001346. Read the rest of the article. Posted by César Sánchez.
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Twisted Bacteria | twistedbacteria.blogspot.com Reviews

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Aug 13, 2012. Keeping harmful protein fibres at bay. Misfolded proteins are not just useless — they can be toxic. Some of them form linear aggregates known as amyloid fibres. That can lead to disorders such as Alzheimer’s and Parkinson’s diseases. Writing in PLoS Biology. And colleagues describe a protein machinery that inhibits the formation and helps to dissolve such fibres. Reference (and source of the image):. DOI: 10.1371/journal.pbio.1001346. Read the rest of the article. Posted by César Sánchez.

INTERNAL PAGES

twistedbacteria.blogspot.com twistedbacteria.blogspot.com
1

Cornering multiple sclerosis -- still a long way to go

http://twistedbacteria.blogspot.com/2011/08/cornering-multiple-sclerosis-still-long.html

Aug 25, 2011. Cornering multiple sclerosis - still a long way to go. Is an autoimmune disease of the central nervous system that causes neurological disability in young adults. Several environmental and genetic factors have been linked to the disease, but the precise mechanisms involved, and whether neurological damage precedes inflammation or vice versa, remain unclear. In a recent article published in Nature. Most of which are related to immune system function and, in particular, to T-helper-cell.

2

Streptomyces: they're twisted!

http://twistedbacteria.blogspot.com/2007/08/streptomyces-theyre-twisted.html

Aug 10, 2007. I'm back from vacation, and trying to catch up. Perhaps this is a good moment for a brief, personal overview of Streptomyces. Biology, summarizing some important aspects. Although they may look like molds, Streptomyces. Organisms are bacteria ( eubacteria. There are essential differences at the cell and molecular levels between fungi. And bacteria (which are prokaryotes. The similarities found between streptomycetes and fungi are the result of convergent evolution. Mutants lacking the abili...

3

About

http://twistedbacteria.blogspot.com/p/about-this-blog.html

Hello, my name is César Sánchez. And I'm the author of this blog. Was born in May 2007 with a focus on actinomycetes. A group of microbes that produce many compounds of pharmaceutical interest (such as antibiotics and anticancer drugs). This was my research topic for a long time and seemed the logical start point for my blog. And I are living beings and, naturally, have evolved. At present I am not a researcher. And my main interest is science communication. You can read more about me at my LinkedIn page.

4

Time-lapse photography of growing mould - Amazing video!

http://twistedbacteria.blogspot.com/2011/01/time-lapse-photography-of-growing-mould.html

Jan 24, 2011. Time-lapse photography of growing mould - Amazing video! Please watch the following video made by Nick Lariontsev. And then let me know if you don't think that microbes are fascinating things. The video was made using time-lapse photography. With several fungi as 'actors': apparently, Aspergillus fumigatus. You can see several pictures of the device used to take the photos at Nick's LiveJournal. See, for instance, this one (photo courtesy of Nick Lariontsev):. Posted by César Sánchez. News,...

5

"Hope he's only a Sunday creationist" by G. Trudeau

http://twistedbacteria.blogspot.com/2010/04/hope-hes-only-sunday-creationist-by-g.html

Apr 20, 2010. Hope he's only a Sunday creationist" by G. Trudeau. This comic strip by Garry Trudeau. Was published in 2006, so you may already know it. Here, a doctor offers two antibiotic choices to a patient suffering from tuberculosis (TB). The choice appears to depend on the patient's religious beliefs. I hope the patient chose wisely - for his own benefit and for that of all the people that could be otherwise infected by his spreading of TB microbes. Interestingly, cartoonist Garry Trudeau. AECC) [S...

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Mixotrophy: Who's watching your dishwasher

http://mixotrophy.blogspot.com/2010/07/whos-watching-your-dishwasher.html

Wednesday, July 07, 2010. Who's watching your dishwasher. I followed a link in this Seth Godin blog post. To a video of a presentation. Given by Tim O'Reilly at a recent conference. The theme of the talk was the importance of data and data accessibility to future web based applications. I did not watch the whole thing, but a point he made about 10 minutes into the talk really struck me. He was talking about smart metering of electricity consumption. I recently came across your blog and have been reading ...

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Spirochetes Unwound: Watch videos of the Lyme disease spirochete escaping from the bloodstream of live mice!

http://spirochetesunwound.blogspot.com/2009/01/watch-videos-of-lyme-disease-spirochete.html

Blogging about those twisty bacteria known as spirochetes. Tuesday, January 27, 2009. Watch videos of the Lyme disease spirochete escaping from the bloodstream of live mice! Most pathogenic microbes that cause systemic infections, regardless of their route of host entry, migrate to the circulatory system, which facilitates their spread throughout the body. These invasive microbes, which include the Lyme disease spirochete B. burgdorferi. Fluoresce by transforming the spirochete with a gfp. Green fluoresc...

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Spirochetes Unwound: A new attenuated leptospirosis vaccine protects hamsters from lethal infection by more than one serovar of Leptospira

http://spirochetesunwound.blogspot.com/2011/05/new-attenuated-leptospirosis-vaccine.html

Blogging about those twisty bacteria known as spirochetes. Sunday, May 1, 2011. A new attenuated leptospirosis vaccine protects hamsters from lethal infection by more than one serovar of Leptospira. Scientists have demonstrated that a new attenuated leptospirosis vaccine protects laboratory hamsters from being killed by Leptospira. Even when the challenge and vaccine strains belong to different serovars (immune types). This is exactly what happened to the leptospirosis vaccines that are given to dogs.

spirochetesunwound.blogspot.com spirochetesunwound.blogspot.com

Spirochetes Unwound: March 2013

http://spirochetesunwound.blogspot.com/2013_03_01_archive.html

Blogging about those twisty bacteria known as spirochetes. Wednesday, March 13, 2013. Triggering OspC production in Borrelia burgdorferi. During tick feeding: Is temperature the real signal? Tick, the vector of the Lyme disease spirochete, goes months without a meal. During this time, the Borrelia burgdorferi. Spirochetes living in its midgut live quiet lives, sipping on the tick's antifreeze. And mammalian host proteins. How does B. burgdorferi. Know when to start making these critical proteins? Incubat...

spirochetesunwound.blogspot.com spirochetesunwound.blogspot.com

Spirochetes Unwound: Severe Lyme arthritis: Gagging on GAGs

http://spirochetesunwound.blogspot.com/2014/12/severe-lyme-arthritis-gagging-on-gags.html

Blogging about those twisty bacteria known as spirochetes. Tuesday, December 30, 2014. Severe Lyme arthritis: Gagging on GAGs. Has been mapping genetic variants that make laboratory mice prone to severe Lyme arthritis. One of these variants is described in a paper. The Journal of Clinical Investigation. Earlier this year. The affected gene encodes the enzyme β-glucuronidase, which carries out a critical function in the lysosome. The key to the study was having strains of mice that differed in their susce...

spirochetesunwound.blogspot.com spirochetesunwound.blogspot.com

Spirochetes Unwound: March 2014

http://spirochetesunwound.blogspot.com/2014_03_01_archive.html

Blogging about those twisty bacteria known as spirochetes. Monday, March 10, 2014. Video microscopy of ticks acquiring the Lyme disease spirochete from mice. The bite of an infected Ixodes. Hard tick transmits the Lyme disease spirochete, Borrelia burgdorferi. To humans. Ticks acquire B. burgdorferi. By feeding on reservoir hosts. Colonized with the spirochete. Reservoir hosts include small mammals such as the white-footed mouse, the main reservoir of B. burgdorferi. In the northeastern United States.

spirochetesunwound.blogspot.com spirochetesunwound.blogspot.com

Spirochetes Unwound: "...and a dog with lepto in its pee."

http://spirochetesunwound.blogspot.com/2013/12/and-dog-with-lepto-in-its-pee.html

Blogging about those twisty bacteria known as spirochetes. Monday, December 16, 2013. And a dog with lepto in its pee.". I saw this video over at the Worms and Germs. Blog It's a new take on a popular Christmas carol. Enjoy! On the twelfth day of Christmas my true love gave to me,. Twelve tubs of Purell,. Eleven raccoon roundworms,. Nine hungry hookworms,. Seven cats with ringworm,. Six big fat dog ticks,. Five cats with fleas. Four rats with cowpox. Two toxic turtles,. And a dog with lepto in its pee.

spirochetesunwound.blogspot.com spirochetesunwound.blogspot.com

Spirochetes Unwound: Video microscopy of ticks acquiring the Lyme disease spirochete from mice

http://spirochetesunwound.blogspot.com/2014/03/video-microscopy-of-ticks-acquiring.html

Blogging about those twisty bacteria known as spirochetes. Monday, March 10, 2014. Video microscopy of ticks acquiring the Lyme disease spirochete from mice. The bite of an infected Ixodes. Hard tick transmits the Lyme disease spirochete, Borrelia burgdorferi. To humans. Ticks acquire B. burgdorferi. By feeding on reservoir hosts. Colonized with the spirochete. Reservoir hosts include small mammals such as the white-footed mouse, the main reservoir of B. burgdorferi. In the northeastern United States.

spirochetesunwound.blogspot.com spirochetesunwound.blogspot.com

Spirochetes Unwound: Is sterilizing immunity against Leptospira possible with protein subunit vaccines?

http://spirochetesunwound.blogspot.com/2013/09/is-sterilizing-immunity-against.html

Blogging about those twisty bacteria known as spirochetes. Sunday, September 15, 2013. Is sterilizing immunity against Leptospira. Possible with protein subunit vaccines? Serogroup B, Streptococcus pneumoniae. And other bacterial pathogens (reviewed in this. It's been hard enough to find leptospiral proteins that protect hamsters from lethal disease when tested as vaccines (see this article. For a review), yet Murray and colleagues sought proteins that protected against Leptospira. Colonization, a more d...

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Twisted Bacteria

Aug 13, 2012. Keeping harmful protein fibres at bay. Misfolded proteins are not just useless — they can be toxic. Some of them form linear aggregates known as amyloid fibres. That can lead to disorders such as Alzheimer’s and Parkinson’s diseases. Writing in PLoS Biology. And colleagues describe a protein machinery that inhibits the formation and helps to dissolve such fibres. Reference (and source of the image):. DOI: 10.1371/journal.pbio.1001346. Read the rest of the article. Posted by César Sánchez.

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Get me outta here! Just another WordPress.com site. The Meaning of Happiness Changes Over Your Lifetime. September 23, 2014. Center for Advanced Hindsight. The following is a scientific and personal article written by CAH member Troy Campbell about happiness. One lovely afternoon, I began chatting to my grandpa. I was completely unaware he was about to say something that would change my view of happiness forever. Then he simply answered, My wife. September 19, 2014. June 2, 2011. Tpos sabay pasok ang kal...

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