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2P2I DB Overview
In the very recent years the number of small molecule disrupting protein-protein interactions (PPIs). Has grown rapidly partly due to the improvement of in silico drug discovery methods. PPIs are now considered as the next generation of very promising therapeutic targets ( Roche and Morelli, 2010. Although a lot of PPI inhibitors have been discovered, little is known. About structural parameters that govern the druggability of protein-protein interactions. Different tools have been developed. Have been a...
2P2I database
How to Use the Database. Beta test version (v0.95). Please, Visit our New version (v1.0). Atomic Analysis of Protein-Protein Interfaces with Known Inhibitors: The 2P2I database. Raphael Bourgeas, Marie-Jeanne Basse, Xavier Morelli and Philippe Roche. PLoS ONE 2010;5(3): e9598. Last updated June 2011.
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