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Avraham Pharma | Combatting Neurodegenerative disease

News & Events. A novel drug candidate for Mild Cognitive Impairment. Once daily, oral delivery. A large phase 2 Randomized trial completing recruitment. 2018 Avraham Pharma - Powered by Wordpress.

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Avraham Pharmaceuticals Ltd

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Avraham Pharma | Combatting Neurodegenerative disease | avphar.com Reviews
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News & Events. A novel drug candidate for Mild Cognitive Impairment. Once daily, oral delivery. A large phase 2 Randomized trial completing recruitment. 2018 Avraham Pharma - Powered by Wordpress.
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1 about mci
2 condition
3 diagnosis
4 unmet need
5 ladostigil
6 background
7 preclinical data
8 clinical data
9 mechanism of action
10 publications
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Avraham Pharma | Combatting Neurodegenerative disease | avphar.com Reviews

https://avphar.com

News & Events. A novel drug candidate for Mild Cognitive Impairment. Once daily, oral delivery. A large phase 2 Randomized trial completing recruitment. 2018 Avraham Pharma - Powered by Wordpress.

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Avraham Pharma |  Diagnosis

http://www.avphar.com/about-mci/diagnosis

News & Events. Early diagnosis of MCI is believed to be important as it is hoped that early treatment can stop or at least delay the clinical deterioration from MCI to full AD. Brain tissue in patients with a diagnosis of MCI is less damaged than tissue in patients with a diagnosis of AD. However, the very definition of MCI as a transitional zone between normal aging and diagnoses of dementia is relatively new and only established in the last decade or so as a new concept. MCI is diagnosed when there is.

2

Avraham Pharma |  Background

http://www.avphar.com/ladostigil

News & Events. Ladostigil is a novel drug candidate, designed to provide treatment for Mild Cognitive Impairment (MCI). It has undergone several clinical trials, where it was shown to be safe and well tolerated. Avraham Pharma has extensive IP protection on Ladostigil. Patents are granted in the US and Australia, and are under examination in additional countries. Avraham Pharmaceuticals Closes an Additional Investment Round of Approximately $4.0 Million. February 25, 2016. July 28, 2015.

3

Avraham Pharma |  Clinical Data

http://www.avphar.com/ladostigil/clinical-data

News & Events. Avraham Pharma is currently sponsoring a 36-month multi-center, randomized double-blind placebo-controlled study to evaluate the safety and efficacy of low-dose Ladostigil in patients with mild cognitive impairment (MCI). Ladostigil has the potential to be a disease modifying agent and slow or stop deterioration of MCI into AD. Avraham Pharmaceuticals Closes an Additional Investment Round of Approximately $4.0 Million. February 25, 2016. July 28, 2015.

4

Avraham Pharma |  Company Profile

http://www.avphar.com/about-us/company-profile

News & Events. Avraham has raised $18 million, which it has used to conduct several clinical trials in patients with MCI and Alzheimer’s Disease, supporting the development of its lead product candidate. Key Shareholders in the company include Yissum , Pontifax , CBI, Technion (TRDF) and others. Avraham Pharmaceuticals Closes an Additional Investment Round of Approximately $4.0 Million. February 25, 2016. July 28, 2015. 2016 Avraham Pharma - Powered by Wordpress.

5

Avraham Pharma |  Unmet need

http://www.avphar.com/about-mci/unmet-need

News & Events. There is no proven treatment or therapy for mild cognitive impairment. As MCI is believed to represent an early state of AD, several treatments proposed for AD, such as cholinesterase inhibitors were tried in the thought that they might be useful. Unfortunately, there are now some indications that the opposite may be true, and that cognitive decline of MCI patients may be accelerated by using AD drugs. Adapted from Schneider, L. S. et al. Arch Neurol 2011;68:58-66. In this document, the ag...

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http://cbi.co.il/avraham

Mild Cognitive Impairment (MCI) and early stages of Alzheimer’s disease. Http:/ www.avphar.com. Ladostigil was designed by Professor Marta Weinstock-Rosin, and Professor Moussa B.H. Youdim. The drug substance was first synthesized by Professor Michael Chorev. The company has exclusively licensed the commercial rights to Ladostigil from the Hebrew University of Jerusalem and the Technion Research and Development Foundation.

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Avraham Pharmaceuticals

http://www.biomarketing.co.il/eng/testimonials-2/avraham-pharmaceuticals

Avraham Pharma needed a new website on a tight budget, and decided to work with BioMarketing who offered a full turnkey solution. Half way through the project had to change the whole company’s positioning, and BioMarketing didn’t lose a step, delivering exactly what we needed, on budget and on time. And more than the results we enjoyed the process and would highly recommend it! Yona Geffen, Ph.D, CEO.

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Avraham Pharma | Combatting Neurodegenerative disease

News & Events. A novel drug candidate for Mild Cognitive Impairment. Once daily, oral delivery. A large phase 2 Randomized trial completing recruitment. 2017 Avraham Pharma - Powered by Wordpress.

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News & Events. A novel drug candidate for Mild Cognitive Impairment. Once daily, oral delivery. A large phase 2 Randomized trial completing recruitment. 2018 Avraham Pharma - Powered by Wordpress.

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