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Bortezomib - Proteasome inhibitor for cancer

Proteasome inhibitor drug for treating cancer.

http://www.bortezomib.org/

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Bortezomib - Proteasome inhibitor for cancer | bortezomib.org Reviews

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Proteasome inhibitor drug for treating cancer.

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1

Side effects of bortezomib

http://www.bortezomib.org/effects.htm

Side effects of bortezomib. Like every drug, bortezomib has potential side effects and they differ in nature and intensity in different patients. The following side effects occur in greater than 30% of patients who have taken bortezomib for treatmet of cancer. Most are similar to the side effects of other chemotherapy agents. Peripheral neuropathy: characterized by decreased sensation and paresthesia (numbness and tingling of the hands and feet). Patients have also reported:.

2

About Bortezomib.org

http://www.bortezomib.org/about.htm

This site presents information about the drug Bortezomib. We have no connection to Millenium Pharmaceuticals or any other pharmaceutical company. Consult your doctor for all medical advice. Bortezomib.org is a production of CVax Magazine. We publish it as part of our mission to communicate medical advances to the public. Austin, TX 78755. Info - at - cvax.org. Site last updated: May 14, 2014.

3

Treatment of cancer with bortezomib

http://www.bortezomib.org/treatment.htm

Treatment of cancer with bortezomib. Bortezomib functions as a garbage disposal unit for waste proteins generated within the cells. Bortezomib was designed to inhibit protease. It effectively chokes or blocks the garbage disposal unit, resulting in build-up of waste products which then kill the cell inside which the waste products are built up. It's a very simple and elegant way of killing off the malignant cell. A test using a combination of bortezomib and radiotherapy.

4

Proteasome inhibitors for cancer treatment

http://www.bortezomib.org/proteasome.htm

Bortezomib - A Proteasome Inhibitor. This class of drug,. Proteasome inhibitors, stops proteasomes, which are large protein complexes. Bortezomib was the first Proteasome inhibitor to be approved for use, and the maker, Millenium Pharmaceuticals, brags on its website. That the drug was approved very quickly, only 4 and a half years after the start of clinical trials. Inhibitors are a unique class of anti-cancer drugs and they are under development, particularly for advanced cancer.

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Bortezomib - Proteasome inhibitor for cancer

Bortezomib is a highly selective, reversible inhibitor of the 26S proteasome. This drug is thought to inhibit many proteins (known as proteasomes) that cancer cells need to survive and multiply. It has been shown to have anti-tumor activity in B cell malignancies. Bortezomib binds to the proteasome and does so reversibly (this is a chemical term that means that the bortezomib molecule can come free under different micro-cellular chemical conditions.) Normal healthy (non-cancer) cells are not as prone...

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