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Welcome to Canbex Therapeutics

Canbex Therapeutics is dedicated to treating spasticity in multiple sclerosis (MS) and other disorders. The goal of the Canbex lead programme is to set a new standard in the treatment of spasticity, through improved tolerability.

http://canbex.co.uk/

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Welcome to Canbex Therapeutics | canbex.co.uk Reviews
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Canbex Therapeutics is dedicated to treating spasticity in multiple sclerosis (MS) and other disorders. The goal of the Canbex lead programme is to set a new standard in the treatment of spasticity, through improved tolerability.
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Welcome to Canbex Therapeutics | canbex.co.uk Reviews

https://canbex.co.uk

Canbex Therapeutics is dedicated to treating spasticity in multiple sclerosis (MS) and other disorders. The goal of the Canbex lead programme is to set a new standard in the treatment of spasticity, through improved tolerability.

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1

Canbex Therapeutics – Medical needs

http://canbex.co.uk/medical-need.html

The medical need in MS spasticity. Over 80% of the estimated two million MS patients worldwide suffer from some degree of spasticity. Spasticity causes pain, interferes with activities of daily life such as walking, may cause serious joint damage, and in severe cases can be completely disabling. Spasticity patients may suffer from shortening of muscles, contractures, deformed limbs, pressure sores and pain, and often require limb braces, special wheelchairs and other equipment to relieve pressure.

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Welcome to Canbex Therapeutics

http://canbex.co.uk/index.html

Improving quality of life in multiple sclerosis. For information about our Phase II trial of VSN16R for the treatment of spasticity in people with MS please click here. The company’s lead compound, VSN16R, is currently in a Phase II study to determine its efficacy in relieving spasticity in people with MS. VSN16R was shown to be safe and well tolerated in a Phase I human safety trial in healthy volunteers that was completed in 2014.

3

Canbex Therapeutics – Corporate information

http://canbex.co.uk/corporate-information.html

Canbex was established to develop the VSN compound series, a drug development platform with potential applications in a wide range of therapeutic areas due to its mechanism of action. The lead molecule of the series, VSN16R, is in a Phase II trial for the treatment of spasticity in people with multiple sclerosis. Dr Jesse Schulman, Chief Executive Officer. Dr Keith Powell, Chairman. Dr Jill Makin, Head of Manufacturing. Dr Allison Morgan, Head of Clinical Operations. Pharm-Olam (UK) – Phase IIa.

4

Canbex Therapeutics – News

http://canbex.co.uk/news.html

Canbex Therapeutics announces start of Phase II trial of VSN16R for spasticity. Canbex Therapeutics enters into option agreement with Ipsen. Canbex Therapeutics Ltd appoints a new CMO. Canbex Therapeutics Ltd to Present at Biotech Showcase 2014. Canbex Therapeutics Commences Phase I Clinical Trial of Lead Product VSN16R as a Potential Treatment for Spasticity in Multiple Sclerosis. Canbex Therapeutics Secures TSB Biocatalyst Grant. Canbex Therapeutics Completes £2.1m ($3.2m) Financing Round.

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Canbex Therapeutics – Lead product

http://canbex.co.uk/lead-product.html

Lead product VSN16R now in Phase II trials. VSN16R a novel orally active small molecule compound that is substantially better tolerated than existing anti-spastic agents. VSN16R does not cause the flaccidity, sedation or other cognitive side-effects that are major disadvantages of other available drugs. VSN16R is currently in Phase II testing for the relief of spasticity in people with MS. The trial is being carried out at major medical centres in the UK.

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Merck Ventures | Canbex Therapeutics

http://merck-ventures.com/portfolio/canbex-therapeutics

MS Ventures, Darmstadt. MS Ventures, Amsterdam. MS Ventures, Cambridge. Canbex Therapeutics is dedicated to the development of novel compounds for the treatment of spasticity in multiple sclerosis (MS) and potentially other disorders. The goal of the Canbex program is to set a new standard in the treatment of spasticity, through improved tolerability. Canbex Therapeutics is based in London, UK. Http:/ www.canbex.co.uk. Canbex Therapeutics announces start of Phase II trial of VSN16R for spasticity.

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Welcome to Canbex Therapeutics

Improving quality of life in multiple sclerosis. Canbex Therapeutics is dedicated to treating spasticity in multiple sclerosis (MS) and other disorders. Spasticity is a debilitating and painful symptom that consists of involuntary spasms and stiffness of limbs and torso. The goal of the Canbex lead programme is to improve the lives of people with this serious and incurable disorder, and set a new standard in the treatment of spasticity.

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