www-vendruscolo.ch.cam.ac.uk
The Vendruscolo Laboratory
http://www-vendruscolo.ch.cam.ac.uk/index.html
Centre for Misfolding Diseases. Our research is aimed at understanding the molecular origins of neurodegenerative disorders, including Alzheimer's and Parkinson's diseases, and at opening in this way novel opportunities for drug discovery to prevent, delay or treat these conditions. We have set up an interdisciplinary approach that brings together concepts and methods from chemistry, physics, engineering, genetics and medicine, using a combination of in silico, in vitro and in vivo approaches. A rational...
www-vendruscolo.ch.cam.ac.uk
The Vendruscolo Laboratory
http://www-vendruscolo.ch.cam.ac.uk/people.html
Centre for Misfolding Diseases. Postdoc (faa25@cam.ac.uk). Postdoc (mb2006@cam.ac.uk). PhD Student (anb39@cam.ac.uk). Postdoc (cc536@cam.ac.uk). MPhil Student (skrc2@cam.ac.uk). Postdoc (fe237@cam.ac.uk). PhD Student (rf389@cam.ac.uk). PhD Student (bf267@cam.ac.uk). Visiting Professor (stefano.gianni@uniroma1.it). PhD Student (pj291@cam.ac.uk). Postdoc (pk397@cam.ac.uk). Postdoc (jh884@cam.ac.uk). MPhil Student (gthh3@cam.ac.uk). Postdoc (gp388@cam.ac.uk). PhD Student (ps589@cam.ac.uk).
www-vendruscolo.ch.cam.ac.uk
The Vendruscolo Laboratory
http://www-vendruscolo.ch.cam.ac.uk/publications.html
Centre for Misfolding Diseases. P Flagmeier, G. Meisl, M. Vendruscolo, T. P. J. Knowles, C. M. Dobson, A. K. Buell and C. Galvagnion. Mutations associated with familial Parkinson's disease alter the initiation and amplification steps of alpha-synuclein aggregation. Proc Natl. Acad. Sci. USA, in press. G Fusco, T. Pape, P. Mahou, P. Arosio, A. Rita Costa, G. Kaminski-Schierle, M. Vendruscolo, G. Veglia, C. M. Dobson and A. De Simone. Structural basis of synaptic vesicle assembly promoted by alpha-synuclein.