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Hetz Lab | Laboratory of Cellular Stress and Biomedicine

Our laboratory was recently awarded with two important grants from the Muscular Dystrophy Association and the ALS Therapy Alliance (USA) to investigate what is the contribution of protein folding stress to sporadic and familial ALS View More. On a recent study published in Science signaling, we have identified through a functional genomic screening new components of the UPRosome signaling platform. This study was highlighted in the cover View More.

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Hetz Lab | Laboratory of Cellular Stress and Biomedicine | ecb-icbm.med.uchile.cl Reviews
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Our laboratory was recently awarded with two important grants from the Muscular Dystrophy Association and the ALS Therapy Alliance (USA) to investigate what is the contribution of protein folding stress to sporadic and familial ALS View More. On a recent study published in Science signaling, we have identified through a functional genomic screening new components of the UPRosome signaling platform. This study was highlighted in the cover View More.
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Hetz Lab | Laboratory of Cellular Stress and Biomedicine | ecb-icbm.med.uchile.cl Reviews

https://ecb-icbm.med.uchile.cl

Our laboratory was recently awarded with two important grants from the Muscular Dystrophy Association and the ALS Therapy Alliance (USA) to investigate what is the contribution of protein folding stress to sporadic and familial ALS View More. On a recent study published in Science signaling, we have identified through a functional genomic screening new components of the UPRosome signaling platform. This study was highlighted in the cover View More.

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Data Repository | Hetz Lab | Laboratory of Cellular Stress and Biomedicine

http://ecb-icbm.med.uchile.cl/data.php

With the aim of providing additional information related to our lab publications, here we have generated a data repository were full scans of Western blots and agarose gels are provided. This will help our colleagues troubleshooting antibodies and also observing raw data of cropped gels. Rodriguez D.,. BH3-only proteins are part of a regulatory network that control the sustained signaling of the Unfolded Protein Response sensor IRE1. Vidal R.,. Hum Mol. Gen. Rojas-Rivera D.,. Zamorano S.,. 3, e272 *#.

2

Publications | Hetz Lab | Laboratory of Cellular Stress and Biomedicine

http://ecb-icbm.med.uchile.cl/publications.php

PUBLICATIONS, REVIEWS AND BOOK CHAPTERS. Publications with affiliation to the University of Chile. Martínez G., Vidal R., Mardones P., Serrano F., Ardiles A., Wirth C., Valdés P., Thielen P., Schneider B., Kerr B., Valdés J., Palacios A., Inestrosa N., Glimcher L.H. and Hetz C. Regulation of memory formation by the transcription factor XBP1. ALS-linked Protein Disulfide Isomerase Variants cause motor dysfunction. And Court F. (2016). Duran-Aniotz C., Cornejo V., and Hetz C. And Vidal R. (2016). Guideline...

3

Funding | Hetz Lab | Laboratory of Cellular Stress and Biomedicine

http://ecb-icbm.med.uchile.cl/funding.php

FONDAP Geroscience Center for Brain Health and Metabolism. Chilean Government Funding agency FONDECYT. Defining the Contribution of ERp57 mutants to the Pathogenesis of Amyotrophic Lateral Sclerosis. FONDECYT 11150579. 2015-2018. Chilean government funding agency FONDECYT. Role of the Integrated Stress Response in the survival of dopaminergic neurons in pre-clinical models Parkinson’s Disease. FONDECYT 11140738. 2014-2016. Chilean government funding agency FONDECYT. Biomedical Neuroscience Institute (BNI).

4

Press | Hetz Lab | Laboratory of Cellular Stress and Biomedicine

http://ecb-icbm.med.uchile.cl/press.php

The main discoveries obtained from our group have been highlighted in the most prestigious communication media of the country, including El Mercurio, la Tercera, La Segunda, la Cuarta, Diario Financiero, Radio Cooperativa, Diario Metro, Diario La Hora, La Nacion, Radio BioBio, Boletin El Pulso Facultad de Medicina (U Chile), Magazine in Vitro, and many other relevant news papers with massive diffusion in Chile. Centro de parkison de los Said prepara su estreno. El chileno que puede curar la ELA. El 4 de ...

5

People | Hetz Lab | Laboratory of Cellular Stress and Biomedicine

http://ecb-icbm.med.uchile.cl/people.php

Claudio Hetz Ph.D. Full Professor University of Chile. Adjunct Professor Harvard School of Public Health (Boston, MA, USA). Adjunct Professor Buck Institute for Research on Aging (Novato, CA, USA). Deputy Director Neuroscience Biomedical Institute (BNI), Faculty of Medicine, University of Chile. Assocate Investigator FONDAP Center for Geroscience, Brain Health and Metabolism, Santiago, Chile. Director Neurounion Biomedical Foundation. Selected honors and awards. 2012 Awarded with the. 2008 The Eppendorf ...

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Signal Transduction Mediated by Calcium. Cellular Stress and Biomedicine. Basic Concepts in Cell Signaling. Advanced Cell and Molecular Biology. Cell Signaling in Biomedicine. Basic Concepts in Cell Signaling. Advanced Cell and Molecular Biology. Cell Signaling in Biomedicine. English Courses for Graduate Students. Http:/ www.aqll-lab.cl. Http:/ www.fisiologiamuscular.cl. Http:/ www.cellsignalinglab.cl. Http:/ www.ecb-icbm.med.uchile.cl. Novoa Carmen (Accounting Assistant). Molina Carolina (Media Manager).

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Hetz Lab | Laboratory of Cellular Stress and Biomedicine

Our laboratory was recently awarded with two important grants from the Muscular Dystrophy Association and the ALS Therapy Alliance (USA) to investigate what is the contribution of protein folding stress to sporadic and familial ALS View More. On a recent study published in Science signaling, we have identified through a functional genomic screening new components of the UPRosome signaling platform. This study was highlighted in the cover View More.

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