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ex scientia is the first company to develop a systematic approach to tailoring drugs against polypharmacology profiles for superior clinical efficacy. This is achieved by either dialling-in extra desired targets to improve phenotypic response or removing unwanted off-targets to improve safety. We focus on exploiting our advanced design technologies to the development of a portfolio of bispecific drugs that tackle unmet medical need.

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ex scientia | exscientia.co.uk Reviews
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ex scientia is the first company to develop a systematic approach to tailoring drugs against polypharmacology profiles for superior clinical efficacy. This is achieved by either dialling-in extra desired targets to improve phenotypic response or removing unwanted off-targets to improve safety. We focus on exploiting our advanced design technologies to the development of a portfolio of bispecific drugs that tackle unmet medical need.
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ex scientia | exscientia.co.uk Reviews

https://exscientia.co.uk

ex scientia is the first company to develop a systematic approach to tailoring drugs against polypharmacology profiles for superior clinical efficacy. This is achieved by either dialling-in extra desired targets to improve phenotypic response or removing unwanted off-targets to improve safety. We focus on exploiting our advanced design technologies to the development of a portfolio of bispecific drugs that tackle unmet medical need.

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Team — Exscientia Ltd

http://www.exscientia.co.uk/about

Andrew Hopkins - CEO. Adrian Schreyer - Head Molecular Informatics. Mark Swindells - COO. Jérémy Besnard - CTO. Senga Oxenham - Executive Officer. Willem van Hoorn - Head of Chemoinformatics. Richard Cox - Systems Architect. Richard Bickerton - CIO. Andy Bell - Chief Chemist. Richard Bickerton PhD - CIO. Mark Swindells PhD - COO. Prof Andrew Hopkins FRSE FRSC - CEO. Andrew spent 10 years at Pfizer, where he was responsible for establishing new research foci including the concepts of druggability and netw...

2

Bispecifics — Exscientia Ltd

http://www.exscientia.co.uk/bispecifics

Single compounds that independently bind two distinct targets. Most diseases are highly networked, so therapies often need to hit multiple nodes to have a sustainable effect. Furthermore, many drugs have now been shown to hit more than one target, suggesting that this. Is more frequent than previously anticipated. Exscientia have harnessed this knowledge to develop a system to design molecules that explicitly hit more than one target.

3

Portfolio — Exscientia Ltd

http://www.exscientia.co.uk/portfolio

Exscientia Ltd, Lab 12 - Dundee Incubator - James Lindsay Place, DD1 5JJ, United Kingdom.

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News — Exscientia Ltd

http://www.exscientia.co.uk/news

April 26, 2016. Evotec and Exscientia announce partnership to discover bispecific small molecule immuno-oncology therapeutics. April 26, 2016. Evotec AG and Exscientia Ltd today announced a research collaboration with the objective to discover and develop first-in-class bispecific small molecule immuno-oncology therapies. April 26, 2016. November 15, 2015. Exscientia named Young Business of the Year. November 15, 2015. November 15, 2015. October 2, 2015. October 2, 2015. October 2, 2015. September 2, 2015.

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Resources - MicroMatrices

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Frontiers, Not Boundaries. MicroMatrices is ideally situated in the heart of one of the most vibrant centers for biomedical research, as well as design, in the UK/Europe. As active partners within this community, MicroMatrices is positioned at the forefront of its field to bring its clients the benefits of new developments within our biotechnology/biomedical sector. For further insight into our scientific resource base, we provide the following references:. Wwwdrugdiscovery.dundee.ac.uk. On an interactiv...

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Medicines tailored to polypharmacology. Medicines tailored to polypharmacology. The clinical efficacy and safety of a drug is determined by its activity profile across many proteins in the proteome. Is the first company to develop a systematic approach to tailoring drugs against polypharmacology profiles for superior clinical efficacy. This is achieved by either dialling-in extra desired targets to improve phenotypic response or removing unwanted off-targets to improve safety. And in particular a.

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