gentrepid.org

Gentrepid

A new approach to candidate disease gene prediction. Utilizes methodology from the fields of structural bioinformatics and systems biology. Two algorithms are applied: Common Module Profiling ( CMP. And Common Pathway Scanning ( CPS. Is completely novel and is based on the hypothesis that disruption of genes of similar function will lead to the same phenotype. CPS. Assumes that common phenotypes are associated with dysfunction in proteins that participate in the same complex or pathway.

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A new approach to candidate disease gene prediction. Utilizes methodology from the fields of structural bioinformatics and systems biology. Two algorithms are applied: Common Module Profiling ( CMP. And Common Pathway Scanning ( CPS. Is completely novel and is based on the hypothesis that disruption of genes of similar function will lead to the same phenotype. CPS. Assumes that common phenotypes are associated with dysfunction in proteins that participate in the same complex or pathway.

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Gentrepid | gentrepid.org Reviews

https://gentrepid.org

A new approach to candidate disease gene prediction. Utilizes methodology from the fields of structural bioinformatics and systems biology. Two algorithms are applied: Common Module Profiling ( CMP. And Common Pathway Scanning ( CPS. Is completely novel and is based on the hypothesis that disruption of genes of similar function will lead to the same phenotype. CPS. Assumes that common phenotypes are associated with dysfunction in proteins that participate in the same complex or pathway.

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gentrepid.org

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Gentrepid

http://www.gentrepid.org/tutorial.php

Mouse over the image to get a brief description of the different aspects and functions of the Gentrepid. Click on the section in the image for a more detailed tutorial. Protein protein interactions have been extracted from I2D. Metabolic and signalling pathways have been extracted from KEGG and BioCarta. Protein domains have been predicted using the HMMER3.0 with the Pfam library. All database queries are via the PostgreSQL server. The system outputs the list of predicted genes.

2

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http://www.gentrepid.org/run_project.php

Welcome to the quicksearch utility of Gentrepid. Get started by selecting a phenotype:. Or, if you are unsure of what to do, click on the sample button and our preloaded data might help.

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Gentrepid

http://www.gentrepid.org/about_2.php

Is a candidate disease gene tool aimed at researchers looking to narrow down their list of candidate disease genes that are located in their region of interest on the genome that has been found to be associated with a particular phenotype or disease. Different to other candidate disease gene prediction tools? We have shown that the use of independent biological data to make complementary predictions ameliorates the problem of incomplete data coverage. Gentrepid. What are the current database statistics?

4

Gentrepid

http://www.gentrepid.org/GWAS_predictions.php

Candidate disease gene predictions for the WTCCC study. This page uses GWAS data from the WTCCC 1. Study (WTCCC, 2007). The protocol used to generate the candidate disease genes is described in Ballouz et al. (2011). Select a SNP-gene mapping. Type in word(s) to filter on:. Sorry, no results.

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sbinf.org

Structural Bioinformatics Home - Olivia Newton-John Cancer Research Institute, Melbourne Australia.

http://sbinf.org/index.html

Bioinformatics: An important tool in medical research. Medical research has already delivered benefits to the community, but it is probably true to say that we still understand less than 1 percent of our own biology at the molecular level. Understanding anything so complex is beyond the scope of a single researcher. For this reason, computers are becoming increasingly important in medical research and bioinformatics is one area which is already generating results. What is Structural Bioinformatics?

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A new approach to candidate disease gene prediction. Utilizes methodology from the fields of structural bioinformatics and systems biology. Two algorithms are applied: Common Module Profiling ( CMP. And Common Pathway Scanning ( CPS. Is completely novel and is based on the hypothesis that disruption of genes of similar function will lead to the same phenotype. CPS. Assumes that common phenotypes are associated with dysfunction in proteins that participate in the same complex or pathway.

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