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www.hep-art.nl | developed a robust bio-artificial liver system, the AMC-BAL

Developed a robust bio-artificial liver system, the AMC-BAL. Spring naar de primaire inhoud. Spring naar de secundaire inhoud. Hep-Art Medical Devices B.V. is a spin off company of the Academic Medical Center in Amsterdam. To comply with the EU standards and thus replace the pig cells for human cells, we have developed the human liver cell line cBAL 111. And generated a protocol to mature the human HepaRG liver cell line. Showing substantial increased survival time.

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www.hep-art.nl | developed a robust bio-artificial liver system, the AMC-BAL | hep-art.nl Reviews
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Developed a robust bio-artificial liver system, the AMC-BAL. Spring naar de primaire inhoud. Spring naar de secundaire inhoud. Hep-Art Medical Devices B.V. is a spin off company of the Academic Medical Center in Amsterdam. To comply with the EU standards and thus replace the pig cells for human cells, we have developed the human liver cell line cBAL 111. And generated a protocol to mature the human HepaRG liver cell line. Showing substantial increased survival time.
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www.hep-art.nl | developed a robust bio-artificial liver system, the AMC-BAL | hep-art.nl Reviews

https://hep-art.nl

Developed a robust bio-artificial liver system, the AMC-BAL. Spring naar de primaire inhoud. Spring naar de secundaire inhoud. Hep-Art Medical Devices B.V. is a spin off company of the Academic Medical Center in Amsterdam. To comply with the EU standards and thus replace the pig cells for human cells, we have developed the human liver cell line cBAL 111. And generated a protocol to mature the human HepaRG liver cell line. Showing substantial increased survival time.

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Pre-clinical Science | www.hep-art.nl

http://www.hep-art.nl/pre-clinical-science

Developed a robust bio-artificial liver system, the AMC-BAL. Spring naar de primaire inhoud. Spring naar de secundaire inhoud. The AMC-BAL based on pig liver cells has been tested extensively in vitro ( Flendrig 1997. And in vivo both in small animals and in larger animals with acute liver failure (ALF) caused by liver ischemia (LIS) or removal of the liver (anhepatic). A schematic drawing of the extracorporeal circuit based on plasmapheresis is shown in Figure 1. Animal model of ALF. Rats; total LIS.

2

Patient Information | www.hep-art.nl

http://www.hep-art.nl/patient-information

Developed a robust bio-artificial liver system, the AMC-BAL. Spring naar de primaire inhoud. Spring naar de secundaire inhoud. Zone there was a need for 2249 liver transplants in 2006, while only 1277 OLTs were carried out. In the US, probably ALF accounts for about 6% of the OLTs among adults ( Seaberg , 1998. For these reasons our research group has started to apply human liver cell lines with sufficient functionality in the bioreactor. The human liver cell line HepaRG. Strain AJ, Neuberger JM. A b...

3

Publications | www.hep-art.nl

http://www.hep-art.nl/publications

Developed a robust bio-artificial liver system, the AMC-BAL. Spring naar de primaire inhoud. Spring naar de secundaire inhoud. Publications AMC/Hep-Art research group bioartificial liver. Geert A.A. Nibourg, Robert A.F.M. Chamuleau, Thomas M. van Gulik, Ruurdtje Hoekstra, Proliferative human cell sources applied as biocomponent in a bioartificial liver: a review. Expert Opinion on Biol Ther. 2012;12(7): 905-921. PlosOne 2012; 7(6):e38778. Alimentary Pharmaceutical Therapeutics, 2012 ;35: 1245-1256. Ruurd...

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Developed a robust bio-artificial liver system, the AMC-BAL. Spring naar de primaire inhoud. Spring naar de secundaire inhoud.

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Profile | www.hep-art.nl

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Developed a robust bio-artificial liver system, the AMC-BAL. Spring naar de primaire inhoud. Spring naar de secundaire inhoud.

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Developed a robust bio-artificial liver system, the AMC-BAL. Spring naar de primaire inhoud. Spring naar de secundaire inhoud. Hep-Art Medical Devices B.V. is a spin off company of the Academic Medical Center in Amsterdam. To comply with the EU standards and thus replace the pig cells for human cells, we have developed the human liver cell line cBAL 111. And generated a protocol to mature the human HepaRG liver cell line. Showing substantial increased survival time.

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www.hep-art.nl | developed a robust bio-artificial liver system, the AMC-BAL

Developed a robust bio-artificial liver system, the AMC-BAL. Spring naar de primaire inhoud. Spring naar de secundaire inhoud. Hep-Art Medical Devices B.V. is a spin off company of the Academic Medical Center in Amsterdam. To comply with the EU standards and thus replace the pig cells for human cells, we have developed the human liver cell line cBAL 111. And generated a protocol to mature the human HepaRG liver cell line. Showing substantial increased survival time.

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