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Iwata Laboratory

International Society for Eye Research (ISER) XXII Biennial Meeting (2016) in Tokyo, Japan. The Iwata Lab will host the International Society for Eye Research (ISER) Biennial Meeting during September 25-26, 2016 at Keio Plaza Hotel in Shinjuku, Tokyo. Over 120 sessions of basic and translational science in vision and ophthalmology will be presented in English. For more information login to the meeting website at http:/ iserbiennialmeeting2016.org. Asian Eye Genetics Consortium (AEGC).

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Iwata Laboratory | iwata-lab.jp Reviews

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International Society for Eye Research (ISER) XXII Biennial Meeting (2016) in Tokyo, Japan. The Iwata Lab will host the International Society for Eye Research (ISER) Biennial Meeting during September 25-26, 2016 at Keio Plaza Hotel in Shinjuku, Tokyo. Over 120 sessions of basic and translational science in vision and ophthalmology will be presented in English. For more information login to the meeting website at http:/ iserbiennialmeeting2016.org. Asian Eye Genetics Consortium (AEGC).

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3 team

4 publication

5 articles

6 photo

7 link

8 activity

9 coming soon

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Iwata Laboratory | iwata-lab.jp Reviews

https://iwata-lab.jp

International Society for Eye Research (ISER) XXII Biennial Meeting (2016) in Tokyo, Japan. The Iwata Lab will host the International Society for Eye Research (ISER) Biennial Meeting during September 25-26, 2016 at Keio Plaza Hotel in Shinjuku, Tokyo. Over 120 sessions of basic and translational science in vision and ophthalmology will be presented in English. For more information login to the meeting website at http:/ iserbiennialmeeting2016.org. Asian Eye Genetics Consortium (AEGC).

INTERNAL PAGES

iwata-lab.jp

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Iwata Laboratory

http://www.iwata-lab.jp/amd.html

Genome Wide Association Study on Wet-Type AMD. Goto A, Akahori A, Okamoto H, Minami M, Terauchi N, Haruhata Y, Obazawa M, Noda T, Honda M, Mizota A, Tanaka M, Hayashi T, Tanito M, Ogata N, and Iwata T. Genetic analysis of typical wet-type age-related macular degeneration and polypoidal choroidal vasculopathy in Japanese population. Journal of Ocular Biology, Disease, and Informatics 2:164-175 (2009). Characterization of Drusen Cynomolgus Monkey. The macaque genome project, which was completed in 2007 gen...

2

Iwata Laboratory

http://www.iwata-lab.jp/gla.html

Characterization of hereditary normal tension glaucoma genes (OPTN, WDR36). Chi Z-L, Yasumoto F, Sergeev Y, Minami M, Obazawa M, Kimura I, Takada Y, and Iwata T. Mutant WDR36 directly affects axon growth of retinal ganglion cells leading to progressive retinal degeneration in mice. Human Molecular Genetics 19:3806-3815 (2010).

3

Iwata Laboratory

http://www.iwata-lab.jp/team.html

Takeshi Iwata, Ph.D. Takeshi.iwata@kankakuki.go.jp. Daisuke Iejima, Ph.D. Akiko Suga, Ph.D. Toshiko Umeda, Ph.D. Toshiko.umeda@kankakuki.go.jp. Brian Rossmiller, Ph.D. Mao Nakayama, M.D. Kazutoshi Yoshitake, Ph.D. Yoshitake.kazutoshi@kankakuki.go.jp. Yuichi Kawamura, M.S. Huiping Li, M.D. Ningxia Eye Hospital, Ningxia Peoople’s Hospital, China. Itaru Kimura, M.D., Ph.D. Department of Ophthalmology, Saitama Medical University. William Sultan, M.D. Charles E. Schmidt College of Medicine (USA).

4

Iwata Laboratory

http://www.iwata-lab.jp/link.html

National Institute of Sensory Organs. International Society for Eye Research. The Association for Research in Vision and Ophthalmology. The American Society of Human Genetics. The American Society for Cell Biology. The Japanese Biochemical Society. The Molecular Biology Society of Japan.

5

Iwata Laboratory

http://www.iwata-lab.jp/hrd.html

Identification of novel mutations in the LRR-cap domain of C21orf2 in Japanese patients with retinitis pigmentosa and cone-rod dystrophy. Cytoplasmic localization of Flag-tagged C21orf2 wild type and mutant proteins. Insert shows overlapping Flag (green) and Tubulin (red) immunostaining. Localization of C21orf2 protein (green) in the photoreceptor connecting cilium indicated by the acetylated Tubulin (red). Dominant mutations in RP1L1 gene are responsible for occult macular dystrophy (Miyake's Disease).

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kankakuki.go.jp

分子細胞生物学研究部

http://www.kankakuki.go.jp/lab_e.html

独立行政法人国立病院機構東京医療センター臨床研究センター感覚器センター. Takeshi Iwata, Director, Division of Molecular and Cellular Biology. 分子細胞生物学研究部では基礎研究者と臨床医が協力して、主に網膜疾患加齢黄斑変性、正常眼圧緑内障、遺伝性網脈絡膜疾患を対象に、病因病態機序の解明を目的として研究しています。我々は感覚器ネットワーク(kankakuki.go.jp)を構築し、国立病院機構や大学病院と連携して、患者様の症例情報と各種体液血液、房水、硝子体、涙液を収集し、遺伝子解析全エクソーム解析、全ゲノム解析、全ゲノム相関解析、蛋白質解析プロテオーム、そしてRNA解析発現解析、マイクロRNA解析によって、発症しやすい体質や発症の時期を予測するための疾患バイオマーカーの探索にも取り組んでいます。また、日本人の加齢黄斑変性、ポリープ状脈絡膜血管症の患者を対象とした全ゲノム相関解析 GWAS)を行い、日本人のリスク遺伝子感受性遺伝子の一つがARMS2/HTRA1であることを明らかにしました。 Nakani...

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International Society for Eye Research (ISER) XXII Biennial Meeting (2016) in Tokyo, Japan. The Iwata Lab will host the International Society for Eye Research (ISER) Biennial Meeting during September 25-26, 2016 at Keio Plaza Hotel in Shinjuku, Tokyo. Over 120 sessions of basic and translational science in vision and ophthalmology will be presented in English. For more information login to the meeting website at http:/ iserbiennialmeeting2016.org. Asian Eye Genetics Consortium (AEGC).

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