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Lumen Therapeutics

Practical application of nitric oxide technology to the treatment of vascular diseases. Lumen Therapeutics is a privately held, development stage biopharmaceutical company focused on proprietary drugs based on oligo-L-arginine. The company's lead product has completed a Phase I/IIa clinical trial for the prevention of vein graft failure after bypass graft surgery. Several additional molecules are in preclinical development. read more. Lumen Therapeutics, LLC.

http://www.lumentherapeutics.com/

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Practical application of nitric oxide technology to the treatment of vascular diseases. Lumen Therapeutics is a privately held, development stage biopharmaceutical company focused on proprietary drugs based on oligo-L-arginine. The company's lead product has completed a Phase I/IIa clinical trial for the prevention of vein graft failure after bypass graft surgery. Several additional molecules are in preclinical development. read more. Lumen Therapeutics, LLC.
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Lumen Therapeutics | lumentherapeutics.com Reviews

https://lumentherapeutics.com

Practical application of nitric oxide technology to the treatment of vascular diseases. Lumen Therapeutics is a privately held, development stage biopharmaceutical company focused on proprietary drugs based on oligo-L-arginine. The company's lead product has completed a Phase I/IIa clinical trial for the prevention of vein graft failure after bypass graft surgery. Several additional molecules are in preclinical development. read more. Lumen Therapeutics, LLC.

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lumentherapeutics.com lumentherapeutics.com
1

Lumen Therapeutics

http://www.lumentherapeutics.com/page/press.htm

Ldquo;L-Arginine polymers enhance coronary flow and reduce oxidative stress following cardiac transplantation in rats” The Journal of Thoracic and Cardiovascular Surgery, 2003; 126:1065-1070; Murray H. Kown, Maarten A. Lijkwan, L. Jahncke, Seiichiro Murata, Jonathan B. Rothbard, Robert C. Robbins. L-Arginine Polymer Mediated Inhibition of Graft Coronary Artery Disease Following Cardiac Transplantation" Transplantation, 2001; 71:1542-1548; Murray H. Kown, Tim van der Steenhoven, Shiro Uemura, Christin...

2

Lumen Therapeutics

http://www.lumentherapeutics.com/page/clinical.htm

The PolyArginine Treated vEiN grafTs (PATENT) study was Lumen's first clinical study. This Lumen sponsored clinical study was a placebo-controlled, double-blinded, and randomized Phase I/IIA study performed at Toronto General Hospital (TGH). TGH is home to the largest open-heart surgery center in Canada and has the best clinical study outcomes of cardiovascular surgery in the country. Study Design: Patients requiring multiple-vein CABG had comparative treatment of LT-1951 and placebo.

3

Lumen Therapeutics

http://www.lumentherapeutics.com/page/cview.htm

Lumen Therapeutics is a privately held, development stage biopharmaceutical company focused on proprietary drugs based on oligo-L-arginine. The company’s lead product has completed a Phase I/IIa clinical trial for the prevention of vein graft failure after bypass graft surgery. Several additional molecules are in preclinical development.

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Lumen Therapeutics

Practical application of nitric oxide technology to the treatment of vascular diseases. Lumen Therapeutics is a privately held, development stage biopharmaceutical company focused on proprietary drugs based on oligo-L-arginine. The company's lead product has completed a Phase I/IIa clinical trial for the prevention of vein graft failure after bypass graft surgery. Several additional molecules are in preclinical development. read more. Lumen Therapeutics, LLC.

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