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http://neosunpharm.com/jsfwDetail1.aspx?id=55

第一组的12例患者用非布索坦40 mg qd,第二组的9例患者用非布索坦80 mg qd。 结果发现,2组基线时平均尿酸值不同 第一组为9.2 mg/dl,第二组为10.4 mg/dl,单独用非布索坦40 mg和80 mg可分别降低尿酸35%和47%。 非布索坦40 mg加lesinurad 400 mg或600 mg可分别降低血尿酸56% 和61%,使尿酸 6及 5 mg/dl的达标率为100%,血尿酸 4 mg/dl的达标率为64%。 非布索坦80 mg加lesinurad 400 mg或600 mg可分别降低血尿酸65%和73%,使血尿酸 6、 5和 4 mg/dl的达标率为100%。 研究结果显示,所有lesinurad与非布索坦联合均可使血尿酸 6 mg/dl的达标率为100%,而单独用非布索坦不能达标,高剂量的联合则使血尿酸 4 mg/dl的达标率达100%,这能加速改善痛风症状,并加速痛风石的溶解。 第一组的12例患者用非布索坦40 mg qd,第二组的9例患者用非布索坦80 mg qd。 Women who cheat on husbands centaurico.com. Drug c...

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