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Hemoglobin X-Ray Structure Solved. HIV Protease Structure Solved, Accelerating Adoption of Structure-based Drug Design. Puts Protein Motion at the Heart of Drug Discovery. Hemoglobin X-Ray Structure Solved. HIV Protease Structure Solved, Accelerating Adoption of Structure-based Drug Design. Puts Protein Motion at the Heart of Drug Discovery. By understanding the motion of a protein, we can realize its therapeutic potential to serve more patients. September 14, 2016.

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Hemoglobin X-Ray Structure Solved. HIV Protease Structure Solved, Accelerating Adoption of Structure-based Drug Design. Puts Protein Motion at the Heart of Drug Discovery. Hemoglobin X-Ray Structure Solved. HIV Protease Structure Solved, Accelerating Adoption of Structure-based Drug Design. Puts Protein Motion at the Heart of Drug Discovery. By understanding the motion of a protein, we can realize its therapeutic potential to serve more patients. September 14, 2016.

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1 approach

2 history

3 team

4 careers

5 news

6 menu

7 drug discovery

8 set in motion

9 a once in a generation

10 paradigm shift

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https://relaytx.com

Hemoglobin X-Ray Structure Solved. HIV Protease Structure Solved, Accelerating Adoption of Structure-based Drug Design. Puts Protein Motion at the Heart of Drug Discovery. Hemoglobin X-Ray Structure Solved. HIV Protease Structure Solved, Accelerating Adoption of Structure-based Drug Design. Puts Protein Motion at the Heart of Drug Discovery. By understanding the motion of a protein, we can realize its therapeutic potential to serve more patients. September 14, 2016.

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relaytx.com

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Relay

http://relaytx.com/news/press-releases

September 14, 2016. Third Rock Ventures Launches Relay Therapeutics with $57 Million Series A Financing to Create Breakthrough Medicines Based on Protein Motion.

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Relay

http://relaytx.com/history

In the early 1990s, the pharmaceutical industry was transformed by the widespread adoption of structure-based drug design a process in which the three-dimensional structure of a given target protein is used to guide the design of drugs that bind to that target. By placing protein motion at the heart of drug discovery, Relay is pursuing what it believes will be a fundamental paradigm shift within the pharmaceutical industry, ushering in a new generation of drugs with the potential to improve and extend th...

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Relay

http://relaytx.com/careers

Our company was founded on the premise that protein motion can be leveraged to create breakthrough medicines. The team at Relay is putting this principle into practice, with the aim of accelerating the development of medicines that will make a transformative difference in patients’ lives. Headquartered in Cambridge, Mass., Relay Therapeutics is a private company launched with $57M Series A financing from Third Rock Ventures and from an affiliate of D. E. Shaw Research. Conduct cell-based assays in suppor...

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Relay

http://relaytx.com/approach

Many drugs are inhibitors that prevent the binding of a ligand to its active site. Relay Therapeutics’ drug discovery engine is built on advances in detecting and characterizing dynamic interactions anywhere on a protein. Not just at the active site. Guide the rational design of allosteric modulators. Detect conformational changes in disease-causing proteins upon drug binding. Perform molecular simulations of unprecedented length and speed using special-purpose supercomputing hardware. September 14, 2016.

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Relay

http://relaytx.com/team

While the Relay Therapeutics team brings a wealth of different experiences to the table, we are united in our mission to bring protein motion to the center of drug discovery. Our roles don’t dictate our daily activities every employee is empowered to make an impact, seize opportunity and to develop skills and expertise. Shuffle for more employee spotlights. Christian Klammt, Ph.D. Alex Taylor, Ph.D. Jim Watters, Ph.D. Randy Kipp, Ph.D. Randy can recite Les Miserables in its entirety. Jeremy once successf...

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Companies | The Jacobson Laboratory at UCSF

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The Jacobson Laboratory at UCSF. Computational structural biology, biophysics, and drug design. Skip to primary content. Matt is a co-founder of. He also serves on the Scientific Advisory Board of Schrodinger LLC, which has commercialized software originally written by him as part of Prime:. The Jacobson lab has also benefited from a long-term collaboration with Pfizer. Blog at WordPress.com.

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Hemoglobin X-Ray Structure Solved. HIV Protease Structure Solved, Accelerating Adoption of Structure-based Drug Design. Puts Protein Motion at the Heart of Drug Discovery. Hemoglobin X-Ray Structure Solved. HIV Protease Structure Solved, Accelerating Adoption of Structure-based Drug Design. Puts Protein Motion at the Heart of Drug Discovery. By understanding the motion of a protein, we can realize its therapeutic potential to serve more patients. September 14, 2016.

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