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SIRTURO™ (bedaquiline) | Official Website | About SIRTURO

SIRTURO Homepage. See full prescribing information including boxed warnings.

http://www.sirturo.com/

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PAGE TITLE
SIRTURO™ (bedaquiline) | Official Website | About SIRTURO | sirturo.com Reviews
<META>
DESCRIPTION
SIRTURO Homepage. See full prescribing information including boxed warnings.
<META>
KEYWORDS
1 SIRTURO
2 bedaquiline
3 TB
4 tuberculosis
5 MDR
6 multi-drug resistant
7 treatment
8 indication
9 use
10 usage
CONTENT
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PAGE
important,safety information,prescribing information,medication guide,medical,information center,email,multi drug resistant tb,about sirturo,sirturo clinical trials,sirturo appropriate use,sirturo,trade;,indications,reserve sirturo,limitations of use
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SIRTURO™ (bedaquiline) | Official Website | About SIRTURO | sirturo.com Reviews

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SIRTURO Homepage. See full prescribing information including boxed warnings.

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1

Clinical Trials |SIRTURO® (bedaquiline) | Official Site

http://www.sirturo.com/sirturo-clinical-trials

FOR HEALTHCARE PROFESSIONALS IN THE US AND PUERTO RICO ONLY. A placebo-controlled, double-blind, randomized trial (Study 1) was conducted in newly diagnosed patients with multi-drug resistant pulmonary Mycobacterium tuberculosis. Patients were randomized to receive treatment with:. Bedaquiline) and other drugs used to treat MDR-TB (SIRTURO. Treatment group) (n=79); or. Placebo plus other drugs used to treat MDR-TB (placebo treatment group) (n=81). Cycloserine/terizidone or available alternative. Time to ...

2

References | SIRTURO® (bedaquiline)

http://www.sirturo.com/references

FOR HEALTHCARE PROFESSIONALS IN THE US AND PUERTO RICO ONLY. American Thoracic Society and Centers for Disease Control and Prevention. Diagnostic Standards and Classification of Tuberculosis in Adults and Children. Am J Respir Crit Care Med. Andries K, Verhasselt P, Guillemont J. A diarylquinoline drug active on the ATP synthase of Mycobacterium tuberculosis. Science. Lalloo UG, Ambaram A. New antituberculous drugs in development. Curr HIV/AIDS Rep. Tuberculosis fact sheet. World Health Organization&...

3

Medical Information Questions | SIRTURO® (bedaquiline)

http://www.sirturo.com/medical-information-center

FOR HEALTHCARE PROFESSIONALS IN THE US AND PUERTO RICO ONLY. Thank you for your interest in contacting Janssen Medical Information. Please note that we can only provide information about products marketed within the United States and must refer international inquiries to our affiliates. For additional information, please visit our website at www.JanssenMD.com/. Janssen Medical Information can be reached by phone at 1-800-JANSSEN. Healthcare professionals can submit questions using the contact us. In the ...

4

Learn about SIRTURO| SIRTURO® (bedaquiline)

http://www.sirturo.com/multidrug-resistant-tb

FOR HEALTHCARE PROFESSIONALS IN THE US AND PUERTO RICO ONLY. The Critical Challenge of Drug Resistance. Anyone can be infected with tuberculosis (TB), but the overall proportion of infected individuals who progress to active disease is approximately 10%. Although efficacious anti-TB drugs have been available for decades, drug resistance in Mycobacterium tuberculosis. Has also been a challenge. TB bacteria can acquire resistance to antibiotics during drug treatment if a patient with TB:. Strains of TB res...

5

Important Safety Information | Warnings | SIRTURO® (bedaquiline)

http://www.sirturo.com/important-safety-information

FOR HEALTHCARE PROFESSIONALS IN THE US AND PUERTO RICO ONLY. Use in Specific Populations. WARNINGS: INCREASED MORTALITY; QT PROLONGATION. An increased risk of death was seen in the SIRTURO. Treatment group (9/79, 11.4%) compared to the placebo treatment group (2/81, 2.5%) in one placebo-controlled trial. Only use SIRTURO. When an effective treatment regimen cannot otherwise be provided. QT prolongation can occur with SIRTURO. An increased risk of death was seen in the SIRTURO. The following may increase ...

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FOR HEALTHCARE PROFESSIONALS IN THE US AND PUERTO RICO ONLY. Is the First Medication for Pulmonary MDR-TB With a Novel Mechanism of Action in Over 40 Years. Bedaquiline) is a diarylquinoline antimycobacterial drug indicated as part of combination therapy in adults (≥18 years) with pulmonary multi-drug resistant tuberculosis (MDR-TB). For use when an effective treatment regimen cannot otherwise be provided. Should be administered by directly observed therapy (DOT). In these settings is not recommended:.

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