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stamlab.org

StamLab

The primary approach of the StamLab is predicated on the use of cutting-edge biochemical, genomic, proteomic and computational approaches in the analysis of regulatory DNA of complex genomes.

http://www.stamlab.org/

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CONTACTS AT STAMLAB.ORG

John Stamatoyannopoulos

WTC Ea●●●●●●te 600

SE●●LE , Washington, 98121

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1.20●●●●3033
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IT Stamlab

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US

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1.20●●●●3033
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IT Stamlab

2211 ●●●●●t Ave

Se●●le , Washington, 98121

US

206.2●●●●●97220
1.20●●●●3033
it@stamlab.org

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StamLab | stamlab.org Reviews
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The primary approach of the StamLab is predicated on the use of cutting-edge biochemical, genomic, proteomic and computational approaches in the analysis of regulatory DNA of complex genomes.
<META>
KEYWORDS
1 stamlab
2 department of
3 genome sciences
4 school of medicine
5 university of washington
6 people
7 publications
8 regulatory dna atlases
9 development and differentiation
10 regulatory networks
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StamLab | stamlab.org Reviews

https://stamlab.org

The primary approach of the StamLab is predicated on the use of cutting-edge biochemical, genomic, proteomic and computational approaches in the analysis of regulatory DNA of complex genomes.

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stamlab.org stamlab.org
1

StamLab

http://www.stamlab.org/topic/regulatory_genomics_of_disease

Altius Institute for Biomedical Sciences. Depts of Genome Science and Medicine. 9650; Back to Main. Gene Regulation and Common Disease. A major focus of the lab is to map the regulatory circuits perturbed by disease-associated variation, and to develop integrated models of common disease that can inform disease diagnosis and therapy. Functional footprinting of regulatory DNA. Large-scale identification of sequence variants influencing human transcription factor occupancy in vivo. Developmental fate and c...

2

StamLab - Publications

http://www.stamlab.org/publications

Altius Institute for Biomedical Sciences. Depts of Genome Science and Medicine. Curr Protoc Mol Biol. J Bioinform Comput Biol. Proc Natl Acad Sci USA. Stem Cells and Dev. February 19, 2015. Cell-of-origin chromatin organization shapes the mutational landscape of cancer. November 20, 2014. A comparative encyclopedia of DNA elements in the mouse genome. November 20, 2014. Conservation of trans-acting circuitry during mammalian regulatory evolution. September 6, 2012. September 6, 2012. September 6, 2012.

3

StamLab

http://www.stamlab.org/topic/regulatory_networks

Altius Institute for Biomedical Sciences. Depts of Genome Science and Medicine. 9650; Back to Main. The combinatorial cross-regulation of hundreds of sequence-specific transcription factors (TFs) defines the core regulatory network of a cell. Such mutual cross-regulation among groups of TFs controls complex functions such as pluripotency and differentiation, and endows a cell with systems-level properties such as robustness and memory. Functional footprinting of regulatory DNA. Coupling transcription fac...

4

StamLab

http://www.stamlab.org/program/roadmap_epigenomics_project

Altius Institute for Biomedical Sciences. Depts of Genome Science and Medicine. Gene Regulation and Common Disease. Functional footprinting of regulatory DNA. Large-scale identification of sequence variants influencing human transcription factor occupancy in vivo. Cell-of-origin chromatin organization shapes the mutational landscape of cancer. A comparative encyclopedia of DNA elements in the mouse genome. Conservation of trans-acting circuitry during mammalian regulatory evolution. 9650; Back to Main.

5

StamLab

http://www.stamlab.org/topic/regulatory_dna_atlases

Altius Institute for Biomedical Sciences. Depts of Genome Science and Medicine. 9650; Back to Main. Functional footprinting of regulatory DNA. Large-scale identification of sequence variants influencing human transcription factor occupancy in vivo. Cell-of-origin chromatin organization shapes the mutational landscape of cancer. A comparative encyclopedia of DNA elements in the mouse genome. Conservation of trans-acting circuitry during mammalian regulatory evolution. Stem Cell Gene Therapy Program.

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LINKS TO THIS WEBSITE

cotsapaslab.info cotsapaslab.info

Projects | Cotsapas Lab

http://www.cotsapaslab.info/projects

Immune-mediated genetics and genomics at Yale and the Broad Institute. Our long-term goal is to understand the mechanisms perturbed by disease risk variants and how these may be targeted for therapy tailored to individual patients’ pathogenic profile. We are particularly interested in diseases of the immune system with special emphasis on the role of immune function in the brain. To achieve this goal we pursue analytical projects grouped into three thematic categories:. We have previously reported that m...

gs.washington.edu gs.washington.edu

UW Genome Sciences: Faculty

http://www.gs.washington.edu/faculty/index.htm

Population genetics and molecular evolution. Akeyj [ a t ] uw.edu. Caberg [ a t ] uw.edu. Computational systems biology; metagenomics; human microbiome; complex networks. Elbo [ a t ] uw.edu. A t ] uw.edu. Proteomics, mass spectrometry and advanced technology development. T ] uw.edu. Yeast genetics and evolution. Maitreya [ a t ] uw.edu. Human genomics and molecular evolution. A t ] gs.washington.edu. Evolution; no longer taking graduate students. A t ] gs.washington.edu. A t ] uw.edu. A t ] uw.edu.

cardiosignal.org cardiosignal.org

CardioSignal WebTools

http://www.cardiosignal.org/links/links.html

The heart of creatures is the foundation of life, the Prince of all, the sun of their microcosm, from where all vigor and strength does flow. - William Harvey, De Motu Cordis, 1628. NAR Database Summary Paper Category List. Regulatory Element Database for. CArdiac Regulatory INteraction database (CARIN). MOODS: Motif Occurrence Detection Suite. Stark Lab Deciphering the transcriptional cis-regulatory code. The Furlong lab: Transcriptional networks. Young Lab, MIT. Stam Lab, university of washington.

gs.washington.edu gs.washington.edu

UW Genome Sciences: Department News

http://www.gs.washington.edu/news/news.htm

Has been awarded a Robert D. Watkins Graduate Research Fellowship from the American Society for Microbiology. Has been awarded the Prix Galien 2015 Pro Bono Humanum Award. Altius Institute for Biomedical Sciences. To be led by Dr. John Stamatoyannopoulos. Has received a Burroughs Wellcome Young Investigator in the Pathogenesis of Infectious Diseases. Has been selected as a Howard Hughes Medical Institute Investigator. Has been named to the American Academy of Arts and Sciences. Has been selected as a rec...

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Gene Regulation and Common Disease. A comparative encyclopedia of DNA elements in the mouse genome. Conservation of trans-acting circuitry during mammalian regulatory evolution. Mouse regulatory DNA landscapes reveal global principles of cis-regulatory evolution. Exonic Transcription Factor Binding Directs Codon Choice and Affects Protein Evolution. Coupling transcription factor occupancy to nucleosome architecture with DNase-FLASH. The accessible chromatin landscape of the human genome.

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