team.gannet53.eu

toc-network.de

Publications [TOC]

http://www.toc-network.de/publications

Surgery at primary versus relapsed epithelial ovarian cancer: a study on aspects of anaesthesiological management. Prognostic and Predictive Value of the Peritoneal Cancer Index in Primary Advanced Epithelial Ovarian Cancer Patients After Complete Cytoreductive Surgery: Study of Tumor Bank Ovarian Cancer. Somatic copy number alterations associated with Japanese or endometriosis in ovarian clear cell adenocarcinoma. Prognostic impact of neuroendocrine differentiation in high-grade serous ovarian carcinoma.

gannet53.eu

Management Structure [GANNET53]

http://www.gannet53.eu/organisation

Project Management Team (PMT). Medical Clinical Trial Manager. Work Package Leaders (WP Leader). External Advisory Board (EAB). Data and Safety Monitoring Committee (DSMC). The Coordinator (Nicole Concin). Nicole Concin, MD. The Project Management Team. The Work Package (WP) Leaders. And the National Trial Group Leaders. Make up the MB. The MB is responsible for monitoring the project progress towards the objectives (deliverables, milestones), ensuring collaboration within and between the WP, coordin...

gannet53.eu

start [GANNET53]

http://www.gannet53.eu/start

A drug strategy targeting stabilised mutant p53 to fight metastatic platinum-resistant ovarian cancer GANNET53 (Ganetespib in metastatic, p53 mutant, platinum-resistant ovarian cancer) is a FP7 research project funded by the European Commission. The project started in October 2013 and aims at improving prognosis and quality of life in platinum-resistant, p53 mutant ovarian cancer patients. The project is planned for 5.5 years with a funding of 6 million Euros.

toc-network.de

start [TOC]

http://www.toc-network.de/start

The Tumor Bank Ovarian Cancer Network (TOC) is a group of dedicated scientists specialized in ovarian cancer research and Rare Gynecological Tumors.

gannet53.eu

imprint [GANNET53]

http://www.gannet53.eu/imprint

Medizinische Universität Innsbruck (MUI). Christoph Probst Platz 1. Tel 43 512 9003 - 0. E-Mail: i-master@i-med.ac.at. Web: http:/ www.i-med.ac.at. Vertreten durch die Rektorin Frau Univ.-Prof. Dr. Helga Fritsch. Die Medizinische Universität Innsbruck ist eine Bildungs- und Forschungseinrichtung. Eine der drei Kernaufgaben der Medizinischen Universität Innsbruck. Technische Umsetzung und Design. Umsatzsteuer-Identifikationsnummer gemäß 27 a Umsatzsteuergesetz: DE 814 804 614. Die Nutzung unserer Webseite...

toc-network.de

Participants List [TOC]

http://www.toc-network.de/participants

Charité - Universitätsmedizin Berlin, Germany - Department of Gynecology. Brief description of the organization. Elena Ioana Braicu MD PhD. Jalid Sehouli, PhD MD Professor. Charité - Universitätsmedizin Berlin, Germany - Department of Pathology. Brief description of the organization. Medizinische Universität Wien , Austria - Molecular Oncology Group. Brief description of the organization. Prof Dr. Robert Zeillinger. Katholieke Universiteit Leuven, Belgium - Department of Gynaecologic Oncology. Oncologica...

gannet53.eu

Project Description [GANNET53]

http://www.gannet53.eu/about

The test drug Ganetespib. Epithelial ovarian cancer (EOC) is the most lethal gyncaecological malignancy causing 41900 deaths annually in Europe. The predominance of aggressive Type II tumours (mainly high-grade serous histology), which are characterised by a high frequency of p53 mutations, and primary or acquired resistance to platinum-based chemotherapy profoundly contribute to the high mortality rate. With current standard therapy the median overall survival of metastatic platinum-resistant ov...Will ...

gannet53.eu

Project Partners No. 1-18 [GANNET53]

http://www.gannet53.eu/consortium

Project Partners No. 1-18. Medizinische Universität Innsbruck Austria (P1 and Coordinator). Katholieke Universiteit Leuven Belgium (P2). Charité - Universitätsmedizin Berlin Germany (P3). Universitätsklinikum Hamburg-Eppendorf Germany (P4). Medizinische Universität Wien Austria (P5). Assistance Publique - Hôpitaux de Paris France (P6). Centre Anticancereux Léon Bérard, Lyon France (P7). AGO Research GmbH Germany (P8). Nord-Ostdeutsche Gesellschaft für Gynäkologische Onkologie - Germany (P9). Four departm...

gannet53.eu

Publications / Press [GANNET53]

http://www.gannet53.eu/activity

CELL DEATH AND DIFFERENTIATION (2016), 1 17: Strong antitumor synergy between DNA crosslinking and HSP90 inhibition causes massive premitoticDNA fragmentation in ovarian cancer cells. Kramer D, Stark N, Schulz-Heddergott R, Erytch N, Edmunds S, Roßmann L, Bastians H, Concin N, Moll UM, Dobbelstein M. doi: 10.1038/cdd.2016.124. [Epub ahead of print] PMID: 27834954;. Press release by Medical University of Innsbruck Innovative Behandlung von Eierstockkrebs: Erste Ergebnisse bei EU-Projekt GANNET53 [Innovati...