www-gene.cimr.cam.ac.uk

JDRF/Wellome Trust Diabetes and Inflammation Laboratory: Homepage

Diabetes and Inflammation Laboratory. Diabetes and Inflammation Laboratory. Interaction of a human T regulatory cell. Blue) and dendritic cell receptor CD80. Red) involving the type 1 diabetes. Susceptibility receptor CTLA-4 (green). In the immunological synapse (yellow). Image courtesy of Paul MacAry. Job vacancies and studentships. Clinical Trials Type1 Diabetes. Cambridge Biomedical Research Centre. Cambridge Institute for Medical Research. National Institute for Health Research (NIHR). Information pr...

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JDRF/Wellome Trust Diabetes and Inflammation Laboratory: Homepage | www-gene.cimr.cam.ac.uk Reviews

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Diabetes and Inflammation Laboratory. Diabetes and Inflammation Laboratory. Interaction of a human T regulatory cell. Blue) and dendritic cell receptor CD80. Red) involving the type 1 diabetes. Susceptibility receptor CTLA-4 (green). In the immunological synapse (yellow). Image courtesy of Paul MacAry. Job vacancies and studentships. Clinical Trials Type1 Diabetes. Cambridge Biomedical Research Centre. Cambridge Institute for Medical Research. National Institute for Health Research (NIHR). Information pr...

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4 introduction and staff

5 publications and data

6 data access/software

7 sample access

8 news

9 cambridge bioresource

10 cambridge immunology

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JDRF/Wellome Trust Diabetes and Inflammation Laboratory: Homepage | www-gene.cimr.cam.ac.uk Reviews

https://www-gene.cimr.cam.ac.uk

Diabetes and Inflammation Laboratory. Diabetes and Inflammation Laboratory. Interaction of a human T regulatory cell. Blue) and dendritic cell receptor CD80. Red) involving the type 1 diabetes. Susceptibility receptor CTLA-4 (green). In the immunological synapse (yellow). Image courtesy of Paul MacAry. Job vacancies and studentships. Clinical Trials Type1 Diabetes. Cambridge Biomedical Research Centre. Cambridge Institute for Medical Research. National Institute for Health Research (NIHR). Information pr...

INTERNAL PAGES

www-gene.cimr.cam.ac.uk

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JDRF/WT DIL: data access

https://www-gene.cimr.cam.ac.uk/data

Diabetes and Inflammation Laboratory. Diabetes and Inflammation Laboratory. Job vacancies and studentships. We are committed to sharing results and experimental data where possible. Taking as an example the genome-wide association studies and follow-up reported in:. A full list of associations, and genes within the LD blocks of those associations is found in our genomic browser T1DBase. And genotype data is available on completion of a Data Access Agreement. A more recent paper:. A human data page. Histo...

2

JDRF/WT DIL: sample access

https://www-gene.cimr.cam.ac.uk/samples

Diabetes and Inflammation Laboratory. Diabetes and Inflammation Laboratory. Job vacancies and studentships. Samples for the case. DNA collections are available, as are cell lines. Completion of a straightforward Material Transfer Agreement is the only requirement - see model agreement. This is an extension of the MTA used for service contracts. For links to other sample collections referenced in our publications. Please see our DNA references and sample sources.

3

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory: Homepage

https://www-gene.cimr.cam.ac.uk/index.shtml

Diabetes and Inflammation Laboratory. Diabetes and Inflammation Laboratory. Interaction of a human T regulatory cell. Blue) and dendritic cell receptor CD80. Red) involving the type 1 diabetes. Susceptibility receptor CTLA-4 (green). In the immunological synapse (yellow). Image courtesy of Paul MacAry. Job vacancies and studentships. Clinical Trials Type1 Diabetes. Cambridge Biomedical Research Centre. Cambridge Institute for Medical Research. National Institute for Health Research (NIHR). Information pr...

4

JDRF/WT DIL: publications & data

https://www-gene.cimr.cam.ac.uk/publications

Diabetes and Inflammation Laboratory. Diabetes and Inflammation Laboratory. Job vacancies and studentships. Including which SNPs have been typed. Available via a Data Access Agreement. T1D Prevention Cambridge Workshop 20/21 October 2010. 2013 JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Cambridge Biomedical Campus, Wellcome Trust/MRC Building, Hills Road, Cambridge, CB2 0XY.

5

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory: Homepage

https://www-gene.cimr.cam.ac.uk/todd

Diabetes and Inflammation Laboratory. Diabetes and Inflammation Laboratory. Interaction of a human T regulatory cell. Blue) and dendritic cell receptor CD80. Red) involving the type 1 diabetes. Susceptibility receptor CTLA-4 (green). In the immunological synapse (yellow). Image courtesy of Paul MacAry. Job vacancies and studentships. Clinical Trials Type1 Diabetes. Cambridge Biomedical Research Centre. Cambridge Institute for Medical Research. National Institute for Health Research (NIHR). Information pr...

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childhood-diabetes.org.uk

UK Children's Diabetes Research: UK GRID: Genetic Resource Investigating Diabetes

http://www.childhood-diabetes.org.uk/grid.shtml

UK Children's Diabetes Research. UK GRID: Genetic Resource Investigating Diabetes. What is the UK GRID? National DNA Collection - The Genetics of Type 1 Diabetes. Aims of the study. Access to data and samples. Oxford Regional Prospective Study, ORPS and Nephropathy Family Study, NFS. What is the UK GRID? Professor David Dunger) and Medical Genetics. In the Cambridge Institute for Medical Research. Professor John Todd) and is funded by the Juvenile Diabetes Research Foundation ( International link. We aim...

clinical-trials-type1-diabetes.com

Healthcare Professionals | DILT1D

http://www.clinical-trials-type1-diabetes.com/healthcare-professionals

If you’re a healthcare professional and require further information or would like to refer a patient please contact Dr Frank Waldron-Lynch. ClinicalTrials.gov Identifier: NCT02265809. UK Clinical Research Network: 17571. Heywood J, Evangelou M, Goymer D, et al. Effective recruitment of participants to a phase I study using the internet and publicity releases through charities and patient organisations: analysis of the adaptive study of IL-2 dose on regulatory T cells in type 1 diabetes (DILT1D). By the S...

clinical-trials-type1-diabetes.com

Home | DILT1D

http://www.clinical-trials-type1-diabetes.com/home

This research is sponsored by Cambridge University Hospitals NHS Foundation Trust. And the University of Cambridge. With funding from a grant provided to the JDRF /Wellcome Trust Diabetes and Inflammation Laboratory (DIL). By the Sir Jules Thorn Charitable Trust. Contributions also acknowledged from the NIHR Cambridge BioMedical Research Centre.

clinical-trials-type1-diabetes.com

About DILfrequency | DILT1D

http://www.clinical-trials-type1-diabetes.com/about-us-2

Aptive study of IL. On regulatory T cells in T. Type 1 diabetes is the most common severe chronic autoimmune disease worldwide and the incidence of the disease is rising rapidly. Type 1 diabetes causes the immune system to mistake cells in the pancreas as harmful and attack them. When these cells are damaged the pancreas is unable to produce insulin, which plays an essential role in transferring glucose out of the bloodstream and into cells to be converted into energy. Page or watch the videos below.

clinical-trials-type1-diabetes.com

Study Location | DILT1D

http://www.clinical-trials-type1-diabetes.com/study-location

The main study visits will be held at the NIHR Wellcome Trust Clinical Research Facility. Level 5), Box 127, Addenbrooke’s Hospital, Cambridge, CB2 0QQ. The NIHR Wellcome Trust Clinical Research Facility is located within the Addenbrooke’s Centre for Clinical Investigation (ACCI) building on the Addenbrooke’s hospital site. For more information about getting to Addenbrooke’s Hospital. This page also includes information on parking and bus timetables. And the University of Cambridge.

clinical-trials-type1-diabetes.com

The Team | DILT1D

http://www.clinical-trials-type1-diabetes.com/the-team

To contact a member of the team please email: DILT1D@cimr.cam.ac.uk. Or telephone 01223 762327. Websites: http:/ www.immunology.cam.ac.uk/directory/Frank.Waldron-Lynch@cimr.cam.ac.uk. Https:/ www-gene.cimr.cam.ac.uk/. Website: http:/ www.immunology.cam.ac.uk/directory/truman. Mark Evans is a Clinical Lecturer and Researcher at The Institute of Metabolic Science, University of Cambridge and Honorary Consultant Physician at Addenbrooke’s Hospital. He specialises in the treatment of type 1 diabetes and ...

clinical-trials-type1-diabetes.com

Am I Eligible? | DILT1D

http://www.clinical-trials-type1-diabetes.com/am-i-eligible

You may be eligible to participate in the DILfrequency if you:-. 8211; Are aged 18-70 and. 8211; Diagnosed with type 1 diabetes in the past 5 years. To register your interest in the study or receive further information please call or email the DILfrequency team at DILT1D@cimr.cam.ac.uk. Page The chief investigator Dr Frank Waldron-Lynch. Or a member of the DILfrequency team will be in touch. This research is sponsored by Cambridge University Hospitals NHS Foundation Trust. And the University of Cambridge.

clinical-trials-type1-diabetes.com

Previous Studies | DILT1D

http://www.clinical-trials-type1-diabetes.com/previous-studies

Aptive study of IL. 2 dose on regulatory T. Cells in type 1. Type 1 diabetes is the most common severe chronic autoimmune disease worldwide and the incidence of the disease is rising rapidly. Type 1 diabetes causes the immune system to mistake cells in the pancreas as harmful and attack them. When these cells are damaged the pancreas is unable to produce insulin, which plays an essential role in transferring glucose out of the bloodstream and into cells to be converted into energy. Waldron-Lynch F, Karec...

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www-gene.cimr.cam.ac.uk

JDRF/Wellome Trust Diabetes and Inflammation Laboratory: Homepage

Diabetes and Inflammation Laboratory. Diabetes and Inflammation Laboratory. Interaction of a human T regulatory cell. Blue) and dendritic cell receptor CD80. Red) involving the type 1 diabetes. Susceptibility receptor CTLA-4 (green). In the immunological synapse (yellow). Image courtesy of Paul MacAry. Job vacancies and studentships. Clinical Trials Type1 Diabetes. Cambridge Biomedical Research Centre. Cambridge Institute for Medical Research. National Institute for Health Research (NIHR). Information pr...

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