alexandershearer.com

Alexander Shearer | Science! (and other good things)

And other good things). There are all these *other* genes that matter. In our work on orphan enzymes. We’ve consistently seen a “rich get richer” effect. Research tends to accumulate on those proteins that already have assigned sequences. This is a systematic issue, since annotation based on sequence similarity probably. We saw this occasionally in the generally awesome BRENDA. Enzyme database. A curator had assigned a sequence to an orphan enzyme when that sequence was actually for a highly similar.

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Alexander Shearer | Science! (and other good things) | alexandershearer.com Reviews

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And other good things). There are all these *other* genes that matter. In our work on orphan enzymes. We’ve consistently seen a “rich get richer” effect. Research tends to accumulate on those proteins that already have assigned sequences. This is a systematic issue, since annotation based on sequence similarity probably. We saw this occasionally in the generally awesome BRENDA. Enzyme database. A curator had assigned a sequence to an orphan enzyme when that sequence was actually for a highly similar.

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1 alexander shearer

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4 publications

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8 no comments yet

9 here’s figure 1

10 the full citation

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Alexander Shearer | Science! (and other good things) | alexandershearer.com Reviews

https://alexandershearer.com

And other good things). There are all these *other* genes that matter. In our work on orphan enzymes. We’ve consistently seen a “rich get richer” effect. Research tends to accumulate on those proteins that already have assigned sequences. This is a systematic issue, since annotation based on sequence similarity probably. We saw this occasionally in the generally awesome BRENDA. Enzyme database. A curator had assigned a sequence to an orphan enzyme when that sequence was actually for a highly similar.

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clovercollective.com

About | Clover Collective

http://www.clovercollective.com/about

We are interested in a wide variety of interdisciplinary projects rooted in biology, including those that may not fit into the research portfolio of traditional academic research institutes. Learn more about our:. We are experienced lab and computational biologists, with a unique perspective derived from a synthesis of biology and design training. We welcome projects in a wide range of technical and subject matter areas. Bioinformatics / computational biology algorithm design. Alexander Shearer is a syst...

orphanenzymes.org

People - Orphan Enzyme Project

http://www.orphanenzymes.org/people

What’s an orphan? The Current OEP Team:. Alexander G. Shearer (PI). Former OEP Team Members:. From the research community:. Kristian B. Axelsen. Alexander G. Shearer (PI). Alex comes to the project from Clover Collective. Find Alex’s papers via PubMed. Alex’s personal website. Describing the combined literature, patent, and database search that netted us over 270 orphan sequences. Tomer is currently a grad student in the Biomedical Informatics. Find Tomer’s papers via PubMed. Christine’s work includes de...

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Alexander Shearer | Science! (and other good things)

And other good things). There are all these *other* genes that matter. In our work on orphan enzymes. We’ve consistently seen a “rich get richer” effect. Research tends to accumulate on those proteins that already have assigned sequences. This is a systematic issue, since annotation based on sequence similarity probably. We saw this occasionally in the generally awesome BRENDA. Enzyme database. A curator had assigned a sequence to an orphan enzyme when that sequence was actually for a highly similar.

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