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ORYX Medicine - Oryx Translational Medicine

ORYX Translational Medicine identifies, finances and develops promising cancer immunotherapy projects in indications with high unmet medical need.

http://www.oryx-medicine.info/

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PAGE TITLE
ORYX Medicine - Oryx Translational Medicine | oryx-medicine.info Reviews
<META>
DESCRIPTION
ORYX Translational Medicine identifies, finances and develops promising cancer immunotherapy projects in indications with high unmet medical need.
<META>
KEYWORDS
1 translational medicine
2 oncology
3 cancer
4 immunotherapy
5 glioblastoma multiforme
6 HPV-associated cancer
7 colorectal cancer
8 oncolytic virus
9 therapeutic vaccine
10 German Cancer Research Center (DKFZ)
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transational medicine oryx,menu,team,advisors,development programs,parvovirus h1,vaccine p16,vaccine msi,partners,academia,business development,news,publications,conferences,translational medicine,oncolytic virus,source dkfz,therapeutic vaccines,imprint
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ORYX Medicine - Oryx Translational Medicine | oryx-medicine.info Reviews

https://oryx-medicine.info

ORYX Translational Medicine identifies, finances and develops promising cancer immunotherapy projects in indications with high unmet medical need.

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oryx-medicine.info oryx-medicine.info
1

ORYX Medicine - Company

http://www.oryx-medicine.info/company

ORYX identifies and develops highly innovative translational projects from academia addressing cancer indications with high unmet medical need. The Company invests in promising R&D projects and develops these to clinical proof of concept prior to partnering for further clinical development and commercialization. ORYX is financed by a group of highly motivated private investors.

2

ORYX Medicine - Academia

http://www.oryx-medicine.info/partners/academia

A distinguished research network, based on exclusive license and cooperation agreements, grants ORYX access to unique competences in the scientific and clinical field. Additionally, it guarantees targeted research in order to expand the company’s activities and grow its project portfolio. German Cancer Research Center (DKFZ), Heidelberg. ORYX is collaborating particularly with Prof. Dr. Magnus von Knebel-Doeberitz, Prof. Dr. Andreas Unterberg, Dr. Karsten Geletneky and Prof. Dr&#4...The responsibilities ...

3

ORYX Medicine - Science

http://www.oryx-medicine.info/science

Cancer immunotherapy refers to treatments that harness and enhance the innate powers of the immune system to fight cancer. Based on the immune system’s extraordinary power, its capacity for memory, its exquisite specificity, and its central and universal role in human biology, cancer immunotherapy has the potential to achieve complete or long-lasting remission.

4

ORYX Medicine - Advisors

http://www.oryx-medicine.info/company/advisors

ORYX relies on a first-class senior advisory board made up of internationally renowned experts from science, clinic and industry. Prof Dr. Dr. mult. Harald zur Hausen. Prof Dr. Elke Jäger.

5

ORYX Medicine - Vaccine MSI

http://www.oryx-medicine.info/science/vaccine-msi

Several cancers arise from the lack of DNA mismatch repair (MMR) resulting in the accumulation of thousands of single deletions or insertions at coding microsatellites (MSI-H). These mutations lead to the inactivation of specific proteins and to the expression of frameshift peptides (FSPs). These FSPs are tumor-specific antigens, which are constantly expressed. Therapeutic vaccine MSI is presently being developed through a clinical Phase I/IIa trial to treat MSI-H colorectal cancer patients.

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Taking innovation from lab to patient. Oncolytic viruses infect and lyse tumor cells and evoke a strong anti-tumor immune response. ORYX develops the oncolytic parvovirus H1 (H-1PV) which is a wild type rat virus with effects in a broad range of human tumors. Clinical development began in 2011 and continues to show promising results in terms of safety, efficacy and immune response. CIMT Annual Meeting, Mainz, Germany, 15-17 May 2018. AACR Annual Meeting, Chicago, USA, 14-18 April 2018.

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