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ORYX Medicine - Oryx Translational Medicine

ORYX Translational Medicine identifies, finances and develops promising cancer immunotherapy projects in indications with high unmet medical need.

http://www.oryx-medicine.net/

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ORYX Medicine - Oryx Translational Medicine | oryx-medicine.net Reviews
<META>
DESCRIPTION
ORYX Translational Medicine identifies, finances and develops promising cancer immunotherapy projects in indications with high unmet medical need.
<META>
KEYWORDS
1 translational medicine
2 oncology
3 cancer
4 immunotherapy
5 glioblastoma multiforme
6 HPV-associated cancer
7 colorectal cancer
8 oncolytic virus
9 therapeutic vaccine
10 German Cancer Research Center (DKFZ)
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transational medicine oryx,menu,team,advisors,development programs,parvovirus h1,vaccine p16,vaccine msi,partners,academia,business development,news,publications,conferences,translational medicine,oncolytic virus,source dkfz,therapeutic vaccines,imprint
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ORYX Medicine - Oryx Translational Medicine | oryx-medicine.net Reviews

https://oryx-medicine.net

ORYX Translational Medicine identifies, finances and develops promising cancer immunotherapy projects in indications with high unmet medical need.

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oryx-medicine.net oryx-medicine.net
1

ORYX Medicine - Vaccine MSI

http://www.oryx-medicine.net/science/vaccine-msi

Several cancers arise from the lack of DNA mismatch repair (MMR) resulting in the accumulation of thousands of single deletions or insertions at coding microsatellites (MSI-H). These mutations lead to the inactivation of specific proteins and to the expression of frameshift peptides (FSPs). These FSPs are tumor-specific antigens, which are constantly expressed. Therapeutic vaccine MSI is presently being developed through a clinical Phase I/IIa trial to treat MSI-H colorectal cancer patients.

2

ORYX Medicine - Science

http://www.oryx-medicine.net/science

Cancer immunotherapy refers to treatments that harness and enhance the innate powers of the immune system to fight cancer. Based on the immune system’s extraordinary power, its capacity for memory, its exquisite specificity, and its central and universal role in human biology, cancer immunotherapy has the potential to achieve complete or long-lasting remission.

3

ORYX Medicine - Conferences

http://www.oryx-medicine.net/news/conferences

BIO-Europe, Cologne, 7-9 November 2016. BioPharm America, Boston, 13-15 September 2016. BIO International Convention, San Francisco, 06-09 June 2016. Boston CEO Conference, Boston, 31 May - 01 June 2016. BIO-Europe Spring 2016, Stockholm, 04-06 April 2016. Biotech Showcase 2016, San Francisco, 11-13 January 2016. Oncolytic Virotherapy Summit 2015, San Francisco, 01-03 December 2015. BIO-Europe 2015, Munich, 02-04 November 2015. Sachs Biotech in Europe Forum, Basel, 29-30 September 2015.

4

ORYX Medicine - Company

http://www.oryx-medicine.net/company

ORYX identifies and develops highly innovative translational projects from academia addressing cancer indications with high unmet medical need. The Company invests in promising R&D projects and develops these to clinical proof of concept prior to partnering for further clinical development and commercialization. ORYX is financed by a group of highly motivated private investors.

5

ORYX Medicine - ParvOryx

http://www.oryx-medicine.net/clinical-trials/parvoryx

To treat glioblastoma multiforme. The clinical development of ParvOryx started in Q3 2011. The Phase I/IIa trial is designed to treat patients with primary or recurrent glioblastoma multiforme using parvovirus H1. This trial is open-labeled and conducted at single center. Primary objectives of the trial are safety, maximum tolerated dose, viremia and virus shedding. Secondary objectives are efficacy, progression-free survival up to six months and overall survival.

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Taking innovation from lab to patient. Oncolytic viruses infect and lyse tumor cells and evoke a strong anti-tumor immune response. ORYX develops the oncolytic parvovirus H1 (H-1PV) which is a wild type rat virus with effects in a broad range of human tumors. Clinical development began in 2011 and continues to show promising results in terms of safety, efficacy and immune response. CIMT Annual Meeting, Mainz, Germany, 15-17 May 2018. AACR Annual Meeting, Chicago, USA, 14-18 April 2018.

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Taking innovation from lab to patient. Oncolytic viruses infect and lyse tumor cells and evoke a strong anti-tumor immune response. ORYX develops the oncolytic parvovirus H1 (H-1PV) which is a wild type rat virus with effects in a broad range of human tumors. Clinical development began in 2011 and continues to show promising results in terms of safety, efficacy and immune response. CIMT Annual Meeting, Mainz, Germany, 15-17 May 2018. AACR Annual Meeting, Chicago, USA, 14-18 April 2018.

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ORYX Medicine - Oryx Translational Medicine

Taking innovation from lab to patient. Oncolytic viruses infect and lyse tumor cells and evoke a strong anti-tumor immune response. ORYX develops the oncolytic parvovirus H1 (H-1PV) which is a wild type rat virus with effects in a broad range of human tumors. Clinical development began in 2011 and continues to show promising results in terms of safety, efficacy and immune response. CIMT Annual Meeting, Mainz, Germany, 15-17 May 2018. AACR Annual Meeting, Chicago, USA, 14-18 April 2018.

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